西南医科大学学报2024，Vol.47Issue(2)：104-110,7.DOI:10.3969/j.issn.2096-3351.2024.02.003
耐碳青霉烯肺炎克雷伯菌耐药机制及治疗策略
Drug resistance mechanism and future treatment strategy of carbapenem resistant Klebsiella pneumoniae
摘要
Abstract
With the widespread use of carbapenem antibiotics,carbapenem resistant Klebsiella pneumoniae(CRKP)has be-come an"urgent"global public health priority.CRKP infections are associated with high mortality and CRKP is an important pathogen of nosocomial infections.The main drug resistance mechanism of CRKP is the production of carbapenemase,and the effective antibiot-ics available in clinic are limited.At present,some new antibiotics show high activity and safety against CRKP.In this paper,the mecha-nism of drug resistance and new antimicrobial agents of CRKP were reviewed for clinical reference.关键词
肺炎克雷伯菌/碳青霉烯耐药/耐药机制/治疗策略Key words
Klebsiella pneumoniae/Carbapenem resistance/Drug resistance mechanism分类
医药卫生引用本文复制引用
袁喆,钱克莉,王忠杰..耐碳青霉烯肺炎克雷伯菌耐药机制及治疗策略[J].西南医科大学学报,2024,47(2):104-110,7.基金项目
重庆市自然科学基金(CSTC2009BB5061) （CSTC2009BB5061）
重庆人社局科研基金(09958013) （09958013）
