西南医科大学学报2024，Vol.47Issue(2)：141-146,6.DOI:10.3969/j.issn.2096-3351.2024.02.009
倾向性评分匹配的微创胆囊癌意向性根治术的安全性及有效性
The safety and efficacy of minimally invasive curative-intent resection for gall-bladder carcinoma based on propensity score matching
摘要
Abstract
Objective To explore the safety and efficacy of minimally invasive curative-intent resection for gallbladder carci-noma.Methods The clinicopathological data of 126 patients who underwent curative-intent resection for gallbladder carcinoma in the Department of Hepatobiliary Surgery of First Affiliated Hospital of Xi'an Jiaotong University from January 2022 to August 2023 was ret-rospectively analyzed.There were 38 males patients(30.2%)and 88 females patients(69.8%);age 40 to 88(63.3±8.8)years old;and there were 92 cases in the open surgery group(73.0%)and 34 cases(27.0%)in the minimally invasive surgery group,of which in-cluded 5 cases who underwent robotic-assisted surgery.By comparing the clinicopathological data differences between the open surgery group and the minimally invasive surgery group before and after propensity score matching(1:1 matching),we analyzed the operative time,intraoperative bleeding,intraoperative blood transfusion,number of lymph node dissection,postoperative recovery,occurrence of complications,length of hospital stays,and hospital costs between the two groups.Results There was no statistically significant differ-ence in baseline data between the open surgery group and the minimally invasive surgery group after propensity score matching(P>0.05).The results showed that the minimally invasive surgery group had a longer operation time than that in the open surgery group(314.3±116.5 min vs.234.3±65.2 min,P = 0.001),but there were no statistical differences between the two groups in the intraopera-tive bleeding,intraoperative transfusion of erythrocytes,transfusion of plasma,whether the hepatic hilum was blocked,number of he-patic hilum blocks,duration of hepatic hilum block,number of lymph node dissection,number of positive lymph nodes,and surgical margins(P>0.05);there was no statistically significant difference between the two groups in the occurrence of postoperative complica-tions and those with C-D grading of complications≥grade III(P>0.05);the time for the first postoperative meal and the time for re-moving the drainage tube in the minimally invasive group were shorter than those in the open surgery group(P<0.05);the postopera-tive hospital stay in the minimally invasive surgery group was shorter than that of the open surgery group(7.0 d vs.8.0 d,P = 0.014),and there was no statistically significant difference in the total length of hospital stays and the total hospital costs(P>0.05).Conclu-sion Minimally invasive curative-intent resection of gallbladder carcinoma showed good surgical safety and efficacy,which could help patients recover quickly,and had certain clinical application value.关键词
胆囊癌/微创手术/开腹手术/倾向性评分匹配Key words
Gallbladder carcinoma/Minimally invasive surgery/Open surgery/Propensity score matching分类
医药卫生引用本文复制引用
张东,李起,刘恒超,雷建军,陈晨,耿智敏..倾向性评分匹配的微创胆囊癌意向性根治术的安全性及有效性[J].西南医科大学学报,2024,47(2):141-146,6.基金项目
国家自然科学基金(62076194) （62076194）
陕西省重点研发计划(2021SF-016,2022SF-410,2022-SF-606) （2021SF-016,2022SF-410,2022-SF-606）
