西南医科大学学报2024，Vol.47Issue(2)：180-184,封3,6.DOI:10.3969/j.issn.2096-3351.2024.02.017
近红外克酮酸菁光热剂及其纳米制剂对肿瘤的光热治疗效果
Photothermal Therapeutic Effects of Near-Infrared Croconaine Photosensitiz-ers and Their Nanoformulations on Tumors
摘要
Abstract
Photothermal therapy(PTT)is a kind of tumor treatment that irradiates photothermal agent(PTA)by external light source to convert light energy into heat energy to kill tumor cells.It has the advantages of strong targeting,little invasion and few adverse reactions.Photothermal agent(PTA)is one of the key factors that determine the effect of photothermal therapy.Croconaines(CR)and their nanoparticles have been used as PTA and achieved good PTT effect in tumor in recent years,due to their strong near-infrared(NIR)absorption,high photothermal conversion efficiency and excellent chemical and thermal stability.In this paper,the molecular structures of croconaines used for photothermal therapy reported in the literatures and the effect of structural modification on photother-mal properties were summarized,and the tumor photothermal therapy effect of croconaine nanoparticles was described,which provided new ideas for the development of efficient photothermal diagnosis and treatment reagents.关键词
肿瘤治疗/光热治疗/光热剂/克酮酸菁/纳米制剂Key words
Tumor therapy/Photothermal therapy/Photothermal agents/Croconaines/Nanoparticles分类
医药卫生引用本文复制引用
唐艺洳,李蕙芳,叶梓,杨琳..近红外克酮酸菁光热剂及其纳米制剂对肿瘤的光热治疗效果[J].西南医科大学学报,2024,47(2):180-184,封3,6.基金项目
四川省自然科学基金(2022NSFSC1468) （2022NSFSC1468）
泸州市人民政府-西南医科大学科技战略合作项目(2019LZXNYDZ09) （2019LZXNYDZ09）
四川省大学生创新创业训练计划项目(S202210632137) （S202210632137）
