沈阳医学院学报2024，Vol.26Issue(2)：146-151,6.DOI:10.16753/j.cnki.1008-2344.2024.02.007
冠状动脉非阻塞性心肌梗死患者的临床特点和预后分析
Clinical characteristics and prognosis of patients with myocardial infarction with non-obstructive coronary arteries
范蒙蒙 1张学平 1刘志强1
作者信息
- 1. 新乡市中心医院心血管内科四,新乡医学院第四临床学院,河南 新乡 453000
- 折叠
摘要
Abstract
Objective:To investigate the clinical characteristics of patients with myocardial infarction with non-obstructive coronary arteries(MINOCA)and the risk factors of major adverse cardiovascular events(MACE)within 1 year of follow-up.Methods:A total of 1 866 patients who met the diagnosis of acute myocardial infarction and underwent coronary angiography in the Department of Cardiovascular Medicine of our hospital from Sep 2018 to Sep 2021 were selected.According to the results of coronary angiography,the patients were divided into MINOCA group and myocardial infarction with obstructive coronary artery disease(MI-CAD)group.The clinical characteristics and the occurrence of MACE in the two groups were compared.According to the occurrence of MACE,patients in MINOCA group were divided into MACE group and non-MACE group.Binary logistic regression analysis was used to explore the risk factors for MACE in MINOCA patients.Results:The age of patients in MINOCA group was lower than that in MI-CAD group,and more patients were female(P＜0.05).The risk factors of cardiovascular diseases in MINOCA group were less than those in MI-CAD group(P＜0.05).Some indexes of laboratory were lower than those in MI-CAD group(P＜0.05).Left ventricular ejection fraction(LVEF)were higher than that in MI-CAD group(P＜0.05).Left ventricular end-diastolic inner diameter(LVEDD)was lower than that in MI-CAD group,and the proportion of patients with abnormal ventricular wall motion and high cardiac function grade was lower than that in MI-CAD group,and the difference was statistically significant(P＜0.05).The 1-year follow-up showed no significant difference in the incidence of MACE between the two groups(P=0.115).Binary logistic regression analysis showed that smoking(OR=13.095,95%CI:1.799-7.398)and low LVEF(OR=0.036,95%CI:0.012-0.679)were independent risk factors for MACE in MIONCA patients.Conclusions:MINOCA patients are more common in women,with lower age and fewer cardiovascular risk factors,but the incidence of MACE is not less than that of MI-CAD patients.Smoking and low LVEF are independent risk factors for MACE in MINOCA patients.关键词
冠状动脉非阻塞性心肌梗死/临床特点/主要不良心血管事件/预后Key words
myocardial infarction with non-obstructive coronary arteries/clinical characteristics/major adverse cardiovascu-lar events/prognosis分类
医药卫生引用本文复制引用
范蒙蒙,张学平,刘志强..冠状动脉非阻塞性心肌梗死患者的临床特点和预后分析[J].沈阳医学院学报,2024,26(2):146-151,6.
