食管疾病2024，Vol.6Issue(1)：35-38,4.DOI:10.15926/j.cnki.issn2096-7381.2024.01.007
食管癌术后局限性颈部/上纵隔淋巴结转移再手术效果探讨
Evaluation of Reoperation Value of Local Cervical or Upper Mediastinal Lymph Node Recurrence after Esophageal Cancer Surgery
摘要
Abstract
Objective To investigate the reoperation value of cervical or upper mediastinal lymph node recurrence after esophageal cancer surgery.Methods Prospective collection of 31 postoperative patients with esophageal cancer who underwent reexamination in our department from January 2019 to September 2022,were found to have lymph node metastasis in the neck or upper mediastinum,and CT scan showed no external invasion and could be surgically removed.According to the patient's wishes.16 cases in the observa-tion group were selected for reoperation treatment,with or without adjuvant radiotherapy and chemotherapy after surgery;15 cases in the control group were selected for simple radiotherapy and chemotherapy.Compa-ring the baseline data and follow-up survival between the two groups,the main endpoint of the study was local recurrence and regional recurrence.Results There was no significant difference in baseline data between the two groups of patients.The observation group had 2 cases of cervical lymphatic fistula and 2 cases of re-current laryngeal nerve injury.Hoarseness returned to normal one month later.The average surgical time is 43 minutes,the average postoperative hospitalization time is 5.8 days,and the average hospitalization cost is 15 042 yuan.The survival rate of observation group 1-year was 100%,and the local control rate was 80%.The control group had no postoperative complications,a 1-year survival rate of 93.3%,a local control rate of 46.7%,a relative risk(RR)of 0.5,and an attributed risk(AR)of 0.46.The average length of hospital stay in the control group was 45 days,and the average hospitalization cost was 42 352 yuan.Comparison between two groups showed that the local control rate of observation group 1a was significantly better than that of the control group.Using local re-currence as the study endpoint,Kaplan Meier survival curve was plotted,and the observation group was sig-nificantly better than the control group(P=0.048).Conclusion For cervical or upper mediastinal lymph node metastasisafter esophageal cancer surgery,reoperation is safe,reliable,low cost and high local control rate.关键词
食管肿瘤/淋巴结转移/局部复发/再手术Key words
esophageal neoplasm/lymph node metastasis/local recurrence/reoperation分类
医药卫生引用本文复制引用
朱磊,曹建伟,周福有..食管癌术后局限性颈部/上纵隔淋巴结转移再手术效果探讨[J].食管疾病,2024,6(1):35-38,4.基金项目
安阳市重大科技专项(2022A02SF002) （2022A02SF002）
