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连续性肾脏替代治疗慢性肾衰竭并心衰的临床效果

王淑萍 李凌霄

中国医药科学2024,Vol.14Issue(5):195-198,4.
中国医药科学2024,Vol.14Issue(5):195-198,4.DOI:10.20116/j.issn2095-0616.2024.05.45

连续性肾脏替代治疗慢性肾衰竭并心衰的临床效果

Clinical efficacy of continuous renal replacement therapy for chronic renal failure with heart failure

王淑萍 1李凌霄1

作者信息

  • 1. 甘肃省武威市凉州医院重症医学科,甘肃武威 733000
  • 折叠

摘要

Abstract

Objective To explore the effectiveness of continuous renal replacement therapy in patients with chronic renal failure and heart failure.Methods A total of 80 patients with chronic renal failure and heart failure admitted to Wuwei Liangzhou Hospital from January 2022 to January 2023 were selected.They were divided into two groups using a random number table method,with 40 patients included in each group.The control group received hemodialysis therapy,while the observation group received continuous renal replacement therapy.The total effective rate,renal function indicators,cardiac function indicators,inflammatory factor indicators,and adverse reaction rates were compared between the two groups.Results The total effective rate of the observation group was 97.50%,which was higher than the control group's 82.50%,with statistically significant differences(P<0.05).After treatment,the renal function indicators of the observation group,including blood urea nitrogen(BUN),serum creatinine(Scr),and cysteine C(Cys-C)inhibitor,were lower than those of the control group,with statistically significant differences(P<0.05).After treatment,the left ventricular ejection fraction(LVEF)of the observation group was higher than that of the control group,while the left ventricular end diastolic diameter(LVEDD)and left ventricular end systolic diameter(LVESD)were lower than those of the control group,with statistically significant differences(P<0.05).After treatment,the inflammatory factor indicators of C-reactiveprotein(CRP),interleukin-6(IL-6)and procalcitonin(PCT)in the observation group were lower than those in the control group,with statistically significant differences(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,with statistically significant differences(P<0.05).Conclusion Continuous renal replacement therapy for patients with chronic renal failure and heart failure can improve the overall effective rate,improve renal and cardiac function,reduce the degree of inflammatory response,and has higher safety.

关键词

慢性肾衰竭并心衰/连续性肾脏替代/肾功能/心功能/不良反应

Key words

Chronic renal failure with heart failure/Continuous renal replacement/Renal function/Cardiac function/Adverse reactions

分类

医药卫生

引用本文复制引用

王淑萍,李凌霄..连续性肾脏替代治疗慢性肾衰竭并心衰的临床效果[J].中国医药科学,2024,14(5):195-198,4.

中国医药科学

2095-0616

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