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不同性别脑性瘫痪患儿临床特征的病例系列报告

牛国辉 张萌萌 崔博 朱登纳 李林琛 夏冰 李停停 谢加阳

中国循证儿科杂志2024,Vol.19Issue(1):47-51,5.
中国循证儿科杂志2024,Vol.19Issue(1):47-51,5.DOI:10.3969/j.issn.1673-5501.2024.01.009

不同性别脑性瘫痪患儿临床特征的病例系列报告

Clinical characteristics of children with cerebral palsy based on different genders:A case series report

牛国辉 1张萌萌 1崔博 1朱登纳 1李林琛 1夏冰 1李停停 1谢加阳1

作者信息

  • 1. 郑州大学第三附属医院儿童康复科/河南省小儿脑损伤重点实验室/郑州市儿童脑瘫防治重点实验室 郑州,450052
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摘要

Abstract

Background The clinical manifestations of children with cerebral palsy are diverse,and there are few studies analyzing the characteristics of children with cerebral palsy of different genders with large sample data in China.Objective To explore the gender differences in clinical data of children with cerebral palsy.Design Case series report.Methods General information,perinatal risk factors,and clinical features of children with cerebral palsy who were hospitalized in the Third Affiliated Hospital of Zhengzhou University from January 2019 to February 2022 were retrospectively collected.Main outcome measures Gender differences in clinical features of children with cerebral palsy.Results A total of 486 children with cerebral palsy were included,including 323 males and 163 females.The proportion of cesarean section,premature infants and macrosomia in males was significantly higher than that in females,while the proportion of normal birth weight children was significantly lower than that in females.In the comparison of birth seasons between groups,the proportion of males born in spring was significantly lower than that of females,while the proportion of winter births was significantly higher than that of females.The proportion of pregnancy complication,asphyxia,cerebral hemorrhage,hypoxic-ischemic encephalopathy and hypoglycemia in males was significantly higher than that in females.The proportion of grade Ⅳ and Ⅴ in the Gross Motor Function Classification System was significantly higher than that in females,and the proportion of abnormal white matter in MRI classification was significantly higher than that in female children.Differences were statistically significant across all comparisons.Conclusion There are gender differences in some clinical data of children with cerebral palsy.Most of the children with cerebral palsy are males and the severity is more serious than that of females.

关键词

脑性瘫痪/性别/危险因素/儿童

Key words

Cerebral palsy/Gender/Risk factors/Children

引用本文复制引用

牛国辉,张萌萌,崔博,朱登纳,李林琛,夏冰,李停停,谢加阳..不同性别脑性瘫痪患儿临床特征的病例系列报告[J].中国循证儿科杂志,2024,19(1):47-51,5.

基金项目

国家卫生健康委医院管理研究所项目:ZDSFY-2018-JYB-10 ()

河南省医学科技攻关省部共建项目:SBGJ2018047 ()

中国循证儿科杂志

OA北大核心CSTPCD

1673-5501

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