中国实用妇科与产科杂志2024，Vol.40Issue(3)：362-365,4.DOI:10.19538/j.fk2024030122
子宫颈碘染色成像技术与子宫颈癌前病变相关性研究
Research on the correlation between cervical iodine staining imaging technology and cervical precancerous le-sions
摘要
Abstract
Objective To study the diagnostic value of cervical iodine staining test in colposcopy for cervical precancer-ous lesions,and evaluate the correlation between iodine staining imaging and the degree of cervical lesions.Methods The study included 2163 patients who underwent colposcopy at Peking University First Hospital Cervical Diagnostic and Treatment Center between January and December 2020;according to the group standard of The Diagnosis and Treatment Standard of Cervical Precancerous Lesion,colposcopic diagnosis was made,the biopsy results were recorded and ana-lyzed statistically.Results Of the 2163 patients who underwent colposcopic examination,783 patients underwent biop-sy,and the biopsy rate was 36.20％.Among them,402 had histopathological diagnosed of CIN2+(cervical intraepithelial neoplasia grade 2 or higher),and the incidence of CIN2+was 18.59％.The coincidence rate of colposcopy with biopsy was 83.03％.The sensitivity,specificity,negative predictive value,and positive predictive value of colposcopy and the to-tal matching ratio were 91.54％,87.34％,97.84％,62.27％,and 88.12％,respectively.The incidence of pathological CIN2+was 59.22％in the iodine test when the non-stained pattern was consistent with the vinegar white epithelium,which was significantly higher than the 32.38％in the in-consistent group,and the difference was statistically sig-nificant(P＜0.05).In addition,there were 388 cases of non-stained areas without vinegar or iodine,and 663 cas-es of non-stained areas with iodine,all of which were sus-pected to be seen under normal colposcopy.Conclusions In colposcopy,there is no need to refer to iodine stain-ing imaging patterns when there is no vinegar white epithelium.If vinegar white epithelium appears and the iodine stain-ing pattern is consistent with vinegar white epithelium staining and evenly distributed,there may be CIN2+present.It is recommended to take a biopsy to confirm the diagnosis.If the iodine staining pattern is inconsistent with the vinegar white epithelial staining or unevenly distributed,there may be a risk of high-grade lesions.In this case,careful consideration should be given to biopsy to avoid misdiagnosis.关键词
子宫颈癌筛查/子宫颈癌前病变/阴道镜拟诊/碘染色成像Key words
cervical cancer screening/cervical precancerous lesions/colposcopy diagnosis/iodine staining分类
医药卫生引用本文复制引用
赵健,李俊霞,王婷婷,冯慧,董建新,崔荣荣,董颖,张岩..子宫颈碘染色成像技术与子宫颈癌前病变相关性研究[J].中国实用妇科与产科杂志,2024,40(3):362-365,4.基金项目
国家重点研发计划(2020AAA0105200) （2020AAA0105200）
