中国兽医科学2024，Vol.54Issue(3)：386-392,7.DOI:10.16656/j.issn.1673-4696.2024.0044
长角血蜱Ykt6蛋白抗东方泰勒虫感染的生物学效应
Biological effects of Ykt6 protein from Haemaphysalis longicornis for anti-infection of Theileria orientalis
摘要
Abstract
In order to understand the biological effects of Ykt6 gene on the infection of Theileria orientalis in Haemaphysalis longicornis,this study evaluated the biological effects of Ykt6 protein for survival rate of ticks,and the reproduction rate,infection rate against H.longicornis during the infection process of T.orientalis between wild and cultured H.longicornis.The results showed that the Ykt6 gene was involved in the host parasite interaction between T.orientalis and H.longicornis.The expression level of the Ykt6 gene was closely related to the survival and reproductive ability of the T.orientalis in H.longicornis.When the expression level of this gene decreases,the survival rate and reproductive ability of the T.orientalis significantly decrease.Further research found that the variation of the Ykt6 gene may affect the interaction between T.orientalis and H.longicornis.Some individuals in the wild had mutations in the Ykt6 gene,leading to a significant decrease in the survival and reproductive ability of the T.orientalis in the tick.This discovery suggested that the variation of the Ykt6 gene may be a key factor in the invasion of H.longicornis by T.orientalis.In summary,the Ykt6 gene has a signi-ficant impact on the invasion of H.longicornis by the T.orientalis.By studying the function and variation of the Ykt6 gene,it is possible to gain a deeper understanding of the interaction between T.orientalis and H.longicornis,providing new ideas and methods for controlling the invasion of T.orientalis.This will help to protect human and animal health and balance the ecological environment.关键词
长角血蜱/东方泰勒虫/Ykt6蛋白/感染/生物学效果Key words
Haemaphysalis longicornis/Theileria orientalis/Ykt6 protein/infection/biological effects分类
农业科技引用本文复制引用
罗金,李祥瑞,赵帅阳,车丽妍,严若锋,宋小凯,任巧云,关贵全,殷宏,刘光远..长角血蜱Ykt6蛋白抗东方泰勒虫感染的生物学效应[J].中国兽医科学,2024,54(3):386-392,7.基金项目
国家重点研发计划项目(2021YFD1800101) （2021YFD1800101）
国家寄生虫资源库项目(NPRC-2019-194-30) （NPRC-2019-194-30）
国家肉牛牦牛产业技术体系项目(CARS-37) （CARS-37）
中国农业科学院科技创新工程项目(Y2019YJ07-04,Y2018PT76) （Y2019YJ07-04,Y2018PT76）
