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艾纳香提取物颗粒剂质量的评价

何佳丽 龙利 齐维金 王鲁

中国兽医科学2024,Vol.54Issue(3):410-417,8.
中国兽医科学2024,Vol.54Issue(3):410-417,8.DOI:10.16656/j.issn.1673-4696.2024.0042

艾纳香提取物颗粒剂质量的评价

Quality evaluation of Blumea balsamifera(L.)DC extractive granules

何佳丽 1龙利 1齐维金 1王鲁2

作者信息

  • 1. 贵州大学 药学院,贵州 贵阳 550025||西南特色药用生物资源开发利用教育部工程研究中心,贵州贵阳 550025
  • 2. 西南特色药用生物资源开发利用教育部工程研究中心,贵州贵阳 550025
  • 折叠

摘要

Abstract

To evaluate the quality of Blumea balsamifera(L.)DC extractive granules.The proper-ties,particle size,moisture and solubility of the self-made Blumea balsamifera(L.)DC extract gran-ules were tested according to the methods required by the 2020 edition of the Chinese Pharmacopoeia.The total flavonoid content of the granules was detected by ultraviolet spectrophotometer(UV),and the volatile constituents were detected by gas chromatography(GC),and carried out the granule stability test and the accelerated test under the packaging conditions.The results showed that the granularity was uniform and brownish-yellow.The particle size and solubility were in accordance with the provi-sions of the Pharmacopoeia,but the moisture did not comply with the provisions of the Pharmacopoeia.The contents of total flavonoids,L-borneol,β-caryophyllene,L-camphor and Linalool were 29.31 mg/g,20.52 mg/g,10.41 mg/g,10.02 mg/g and 2.18 mg/g.The volatile constituents were significantly reduced at high temperature,and there is no significant change in the content of the active ingredients in the appearance of high humidity and bright light.The accelerated test results at room temperature under packaging conditions show that there is no obvious change in the appearance characteristics of the par-ticles and the content of the active ingredients.In summary,the granules has good room temperature stability under packaging,which provides data for the establishment of further quality standards for granules.

关键词

艾纳香提取物/颗粒剂/质量

Key words

Blumea balsamifera(L.)DC extractive/granule/quality

分类

农业科技

引用本文复制引用

何佳丽,龙利,齐维金,王鲁..艾纳香提取物颗粒剂质量的评价[J].中国兽医科学,2024,54(3):410-417,8.

基金项目

国家自然科学基金项目(32160849,32273051) (32160849,32273051)

中国兽医科学

OA北大核心CSTPCD

1673-4696

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