中国畜牧杂志2024,Vol.60Issue(4):1-8,8.DOI:10.19556/j.0258-7033.20230313-01
蜂胶中多酚化合物对奶牛乳腺炎的缓解作用及机制研究进展
Recent Progress on Effects and Mechanisms of Propolis Polyphenols on Mastitis in Dairy Cows
摘要
Abstract
Bovine mastitis is an inflammatory disease which caused by various factors including pathogenic infections.The severe mastitis could result in a significant reduction in milk production and quality,further leading to serious economic losses in the dairy industry.Mastitis may be regulated by some signaling pathways such as NF-κB,MAPK,JAK-STAT,PI3K-AKT-mTOR and Nrf2-ARE.Propolis is gathered from plant resin and mixed with the secretion of the worker bees.Propolis riching in polyphenolic compounds has been proven to play an effective role in the prevention of bovine mastitis by killing mastitis pathogens,alleviating inflammation,and acting as a vaccine adjuvant.This article outlines the mechanism of mastitis,and summarizes the effects of propolis extracts and polyphenols on relieving bovine mastitis,which will provide a theoretical basis for better application of propolis polyphenols in the prevention of mastitis in dairy cows.关键词
奶牛乳腺炎/蜂胶/多酚/信号通路Key words
Bovine mastitis/Propolis/Polyphenols/Signaling pathway分类
农业科技引用本文复制引用
祝梅斐,李婧妍,王炳,李珊珊,胡福良..蜂胶中多酚化合物对奶牛乳腺炎的缓解作用及机制研究进展[J].中国畜牧杂志,2024,60(4):1-8,8.基金项目
国家自然科学基金面上项目(31972588) (31972588)
财政部和农业农村部:国家现代农业产业技术体系建设项目(CARS-44) (CARS-44)