肿瘤防治研究2024，Vol.51Issue(3)：157-162,6.DOI:10.3971/j.issn.1000-8578.2024.23.1237
循环肿瘤DNA在结直肠癌精准诊疗中的应用
Application of Circulating Tumor DNA in Precision Diagnosis and Treatment of Colorectal Cancer
杨文涛 1李溟涵 1蔡继东 2李聪 1宋望 1徐烨1
作者信息
- 1. 200032 上海,复旦大学附属肿瘤医院大肠外科,复旦大学上海医学院肿瘤学系
- 2. 200032 上海,复旦大学附属肿瘤医院内镜科,复旦大学上海医学院肿瘤学系
- 折叠
摘要
Abstract
Colorectal cancer(CRC)is one of the most common malignant tumors recorded worldwide.This condition has high morbidity and mortality and seriously endangers people's health.Traditional diagnostic models fail to meet people's current needs for real-time monitoring of tumors.Compared with traditional detection methods,ctDNA detection is not only noninvasive but can also attain real-time detection of comprehensive genomic information of tumors.The advancement of detection technology has gradually highlighted the potential of ctDNA detection in the clinical treatment of CRC.This article reviews the advancements on the clinical application of ctDNA in early screening,minimal residual disease detection,and guidance on individualized treatment of CRC patients.关键词
结直肠癌/循环肿瘤DNA/精准治疗/筛查/疗效评估/耐药/肿瘤复发/预后Key words
Colorectal cancer/Circulating tumor DNA/Precise treatment/Screening/Treatment efficacy evaluation/Drug resistance/Tumor recurrence/Prognosis分类
医药卫生引用本文复制引用
杨文涛,李溟涵,蔡继东,李聪,宋望,徐烨..循环肿瘤DNA在结直肠癌精准诊疗中的应用[J].肿瘤防治研究,2024,51(3):157-162,6.
