安徽中医药大学学报2024,Vol.43Issue(2):14-18,5.DOI:10.3969/j.issn.2095-7246.2024.02.005
胃癌术后胃肠功能障碍的危险因素及芪黄煎剂的作用
Risk Factors for Gastrointestinal Dysfunction After Gastric Cancer Surgery and the Role of Qi-huang Decoction
摘要
Abstract
Objective To investigate the risk factors for gastrointestinal dysfunction after gastric cancer surgery and the role of Qihuang Decoction.Methods Clinical data were collected from 83 patients with gastric cancer who underwent D2 radical sur-gery,and according to the presence or absence of gastrointestinal dysfunction after surgery,they were divided into dysfunction group with 32 patients and non-dysfunction group with 51 patients.A univariate analysis was performed for the clinical data,and the independent factors with P<0.05 were included in the binary logistic regression analysis to investigate the influencing fac-tors for gastrointestinal function after surgery.Results Compared with the non-dysfunction group,the dysfunction group had the independent influencing factors for postoperative gastrointestinal motility:preoperative albumin,tumor size,tumor pTNM pathological stage,tumor cTNM clinical stage,surgical procedure,intraoperative blood loss,and treatment with the traditional Chinese medicine(TCM)Qihuang Decoction(P<0.05).The multivariate regression analysis showed that tumor size,surgical procedure,and intraoperative blood loss were risk factors(P<0.05),while preoperative albumin and TCM treatment with Qi-huang Decoction were protective factors(P<0.05).Conclusion There is a relatively high incidence rate of early gastrointesti-nal dysfunction in patients undergoing surgery.The risk factors that can aggravate gastrointestinal dysfunction should be con-trolled during prevention and treatment,and Qihuang Decoction combined with enteral nutrition should be taken seriously to im-prove the nutritional status of patients.关键词
胃肠功能障碍/芪黄煎剂/手术/影响因素Key words
Gastrointestinal dysfunction Qihuang Decoction/Surgery/Influencing factors分类
医药卫生引用本文复制引用
牛晓勇,于庆生,郑州..胃癌术后胃肠功能障碍的危险因素及芪黄煎剂的作用[J].安徽中医药大学学报,2024,43(2):14-18,5.基金项目
国家自然科学基金项目(82174160) (82174160)
"十二五"国家临床重点专科建设项目(财社[2013]239号) (财社[2013]239号)