NEAT1、miR-27a-3p在阿尔茨海默病患者血清和脑脊液中的表达关系OACSTPCD
Expression relationship and significance of NEAT1 and miR-27a-3p in serum and cerebrospinal fluid of patients with Alzheimer disease
目的:探究长链非编码RNA核富含丰富的转录本1(long chain non-coding RNA nuclear-enriched abundant transcript 1,LncRNA NEAT1)、miR-27a-3p在阿尔茨海默病(Alzheimer disease,AD)患者血清和脑脊液中的表达关系及意义.方法:选择2019年10月至2021年9月天津市第五中心医院神经内科收治的AD患者66例作为病例组,根据临床痴呆评定量表(clin…查看全部>>
Objective:To explore the expression relationship and significance of long chain non-coding RNA nuclear-enriched abundant transcript 1(LncRNA NEAT1)and miR-27a-3p in serum and cerebro-spinal fluid of patients with Alzheimer disease(AD).Methods:Sixty-six AD patients received by the department of neurology of our hospital from October 2019 to September 2021 were gathered,according to the clinical dementia rating scale score,they were grouped into mild group(≤ 1…查看全部>>
何丽杰;张春艳;王静
天津市第五中心医院检验科,天津 300450天津市第五中心医院天津市早产儿器官发育表观遗传重点实验室,天津 300450天津市第五中心医院检验科,天津 300450
临床医学
阿尔茨海默病长链非编码RNA核富含丰富的转录本1miR-27a-3pβ淀粉样蛋白相关性
Alzheimer disease(AD)Long chain non-coding RNA nuclear-enriched abundant transcript 1(LncRNA NEAT1)miR-27a-3pAmyloid β(Aβ)Correlation
《北京大学学报（医学版）》 2024 (2)
207-212,6
天津市科技计划项目(21JCZDJC01270)Supported by the Tianjin Science and Technology Program(21JCZDJC01270)
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