成都中医药大学学报2024，Vol.47Issue(2)：1-10,10.DOI:10.13593/j.cnki.51-1501/r.2024.01.001
基于气相色谱质谱联用技术分析木香及川木香不同炮制品挥发油的化学成分
Chemical Composition of Volatile Oils from Different Processed Products of Aucklandia Lappa Decne.and Vladimiria Souliei(Franch.)Ling Based on Gaschromatography-Mass Spectrometry
摘要
Abstract
Objective:To explore the effect of different processing methods on the volatile oil components of Aucklandia lappa Decne.and Vladimiria souliei(Franch.)Ling.Methods:We use cutting,stir-frying,bran-frying and straw paper-simmering methods to pre-pare the Aucklandia lappa Decne.and Vladimiria souliei(Franch.)Ling,determine the volatile oil content of different preparations.The volatile oil components were studied usinggaschromatography-mass spectrometry.Results:Thirty-eight compounds were identified in the Aucklandia lappa Decne.,while 36,34,and 34 compounds were identified in the stir-fried,bran-fried,and straw paper-wrapped products,respectively.For Vladimiria souliei(Franch.)Ling,32 compounds were identified in the raw product,while 35,35,and 34 compounds were identified in the stir-fried,bran-fried,and straw paper-wrapped products,respectively.After the process-ing of Aucklandia lappa Decne.,the content of some aroma components such as α-phellandrene,sabinene,and caryophyllene de-creased,and the content of medicinal components such as dehydrocostus lactone,caryophyllene oxide and geranylacetone gradually in-creased.The variation of components of Vladimiria souliei(Franch.)Ling was similar to that of Aucklandia lappa Decne.,but the aro-ma components were less.The same components of Aucklandia lappa Decne.and Vladimiria souliei(Franch.)Ling include dehydro-costus lactone,(Z,Z,Z)-heptadeca-1,8,11,14-tetraene,elemene,costol,α-costol.The content difference compounds obtained by orthogonal partial least squares-discriminant analysis included dihydrodehydrocostus lactone,mokkolactone,α-costol,γ-costol,α-ber-gamotenol,naphthalene,(Z,Z,Z)-heptadeca-1,8,11,14-tetraene,α-selinene,2-isopropenyl-4a,8-dimethyl-1,2,3,4,4a,5,6,7-oc-tahydronaphthalene,(3Z,3a R,7a S)-3-ethylidene-1,2,3a,4,5,6,7,7a-octahydroindene and elemene.Conclusion:About60%ofthe components in the volatile oil of Aucklandia lappa Decne.and Vladimiria souliei(Franch.)Ling were approximately same.There were differences in components between Aucklandia lappa Decne.and Vladimiria souliei(Franch.)Ling,and the differences decreased af-ter processing.The straw paper-wrapped method had the greatest effect on the chemical composition of Aucklandia lappa Decne.and Vladimiria souliei(Franch.)Ling.The decrease of pungent compounds and the increase of some active components may be the materi-al basis of relieving diarrhea.关键词
木香/川木香/气相色谱质谱联用法/正交偏最小二乘法判别分析/聚类分析Key words
Aucklandia lappa Decne./Vladimiria souliei(Franch.)Ling/Gaschromatography-mass spectrometry/Orthogonal partial least squares-discriminant analysis/Cluster analysis分类
医药卫生引用本文复制引用
梁淞婷,陈瑞鑫,次仁卓嘎,蒋桂华,杜蕾蕾..基于气相色谱质谱联用技术分析木香及川木香不同炮制品挥发油的化学成分[J].成都中医药大学学报,2024,47(2):1-10,10.基金项目
国家自然科学基金项目(82173928) （82173928）
四川省应用基础研究计划项目(2020YJ0375) （2020YJ0375）
四川省中药研究所基础研究项目(2020JDKY0013) （2020JDKY0013）
四川省中医药管理局项目(2021MS022、2021MS017) （2021MS022、2021MS017）
