腹腔镜外科杂志2024，Vol.29Issue(2)：108-114,7.DOI:10.13499/j.cnki.fqjwkzz.2024.02.108
腹腔镜胆总管探查一期缝合与胆道内支架引流一期缝合疗效比较的Meta分析
Meta-analysis of efficacy comparison between laparoscopic common bile duct exploration with primary suture and biliary drainage stenting with primary suture
摘要
Abstract
Objective:Through meta-analysis,this study compared the clinical efficacy of laparoscopic common bile duct explo-ration(LCBDE)+primary suture(PS)with biliary drainage stenting(BDS)+PS and explored their clinical application value.Methods:The clinical studies comparing the efficacy of LCBDE+PS and LCBDE+BDS+PS in various databases at home and abroad were searched.The search period spanned from Jan.1,2010 to Aug.1,2023.Outcome indicators included operation time,duration of hospita-lization,incidence of postoperative bile leakage and overall complication rate.Relevant data were extracted and analyzed using RevMan 5.4 software.Results:Five retrospective cohort studies meeting the inclusion criteria were included,covering a sample size of 611 cases.There were 292 cases in the PS group,and 319 cases in the BDS+PS group.The results of the meta-analysis indicated no signifi-cant differences in operation time(WMD=-1.66,95%CI=-15.78～12.46,P=0.82),duration of hospitalization(WMD=-0.81,95%CI=-2.23～0.60,P=0.26),residual stone rate(OR=1.45,95%CI=0.24～8.83,P=0.69),and overall complication rate(OR=1.15,95%CI=0.70～1.88,P=0.58)between the two groups.However,the incidence of postoperative bile leakage(OR= 3.63,95%CI=1.77～7.44,P=0.0004)was higher in the PS group than that in the BDS+PS group.Conclusions:For choledocholi-thiasis patients who meet the indications,LCBDE+BDS+PS can reduce the incidence of postoperative bile leakage to a certain extent,which is safe and effective.关键词
胆总管结石病/胆总管探查术/腹腔镜检查/一期缝合/支架/Meta分析Key words
Choledocholithiasis/Common bile duct exploration/Laparoscopy/Primary suture/Stents/Meta-analysis分类
医药卫生引用本文复制引用
郭志唐,龙奎,陈章彬,李伟思,戈佳云..腹腔镜胆总管探查一期缝合与胆道内支架引流一期缝合疗效比较的Meta分析[J].腹腔镜外科杂志,2024,29(2):108-114,7.基金项目
昆明医科大学第二附属医院院内临床研究项目(ynIIT2021013) （ynIIT2021013）
