分析化学2024，Vol.52Issue(3)：439-448,后插1-后插4,14.DOI:10.19756/j.issn.0253-3820.221371
基于碳点与金属有机框架复合材料的葡萄糖直接电化学传感平台
Direct Electrochemical Glucose Sensing Platform Based on Carbon Dots and Metal-Organic Framework Composite Materials
摘要
Abstract
An enzyme-free glucose electrochemical sensor based on carbon dots(CDs)and metal-organic framework(MOF)composites was constructed.Three kinds of carbon dots with different doping elements(C-CDs,B-CDs and N-CDs)were prepared by hydrothermal method,and then combined with ZIF-67 respectively to obtain three kinds of CDs@ZIF-67 composite materials,which were modified on glassy carbon electrode(GCE)to construct highly sensitive enzyme-free glucose electrochemical sensor.The combination of CDs and ZIF-67 could effectively improve the poor electrical conductivity of MOFs,and then improve their catalytic activity toward glucose.When nitrogen element was doped in CDs,nitrogen element induced more defects on CDs surface and speeded up the electron transfer rate.Therefore,N-CDs@ZIF-67 exhibited the best electrocatalytic performance for glucose.N-CDs@ZIF-67/GCE was used to construct an electrochemical sensor,and the response current showed a good linear relationship with the concentration of glucose in the range of 0.1-1000 μmol/L and 1000-7000 μmol/L,respectively,with a detection limit of 31.8 nmol/L(S/N=3).The sensor was successfully applied to detection of glucose in real human serum samples.The recoveries were 101.5%-109.0%,and the relative standard deviations were less than 3.1%.The fabricated sensor exhibited potential practicability for detection of glusose in real samples.关键词
金属有机框架/碳点/葡萄糖/电化学传感器Key words
Metal-organic framework/Carbon dots/Glucose/Electrochemical sensor引用本文复制引用
颜文菊,张子豪,庞元昊,周雪英,王钰,袁亚利..基于碳点与金属有机框架复合材料的葡萄糖直接电化学传感平台[J].分析化学,2024,52(3):439-448,后插1-后插4,14.基金项目
国家自然科学基金项目(No.22364011)资助. Supported by the National Natural Science Foundation of China(No.22364011). （No.22364011）
