影像科学与光化学2024，Vol.42Issue(2)：141-147,7.DOI:10.7517/issn.1674-0475.231027
术前多模态超声参数对乳腺良性结节微波消融术后疗效的预测价值
Predictive Value of Preoperative Multimodal Ultrasound Parameters for Curative Effect on Benign Breast Nodules after Microwave Ablation
摘要
Abstract
Objective:To explore the predictive value of preoperative multimodal ultrasound parameters for curative effect on benign breast nodules after microwave ablation.Methods:A total of 175 patients with benign breast nodules(210 nodules)undergoing elective microwave ablation in the hospital were enrolled between January 2019 and September 2022.According to reduction rate of breast nodules at 3 months after surgery and presence or absence of complete ablation,they were divided into effective group(m=143)and ineffective group(n=32).The clinical data of patients were collected.Before surgery,maximum diameter(Dmax),peak intensity(PI),time to peak(TTP),maximum elasticity of Young's modulus(Emax)and mean elasticity of Young's modulus(Emean)of nodules were recorded by multimodal ultrasound(routine ultrasound,contrast-enhanced ultrasound,ultrasonic elastography).The independent risk factors affecting the curative effect of microwave ablation in patients with benign breast nodules were analyzed by univariate and multivariate Logistic regression analysis.The risk prediction model was constructed,and its predictive efficiency was detected by receiver operating characteristic(ROC)curves.Results:Before surgery,there were significant differences in Dmax,BMI,PI,TTP,Emax and Emean between effective group and ineffective group(P＜0.05),but there was no significant difference in age,marital history or underlying diseases(P＞0.05).Logistic regression analysis showed that preoperative Dmax,PI and Emax were independent risk factors affecting the curative effect of microwave ablation.The probability by risk prediction model was as follow:P=1/(1+e-25.568-4 911×Dmax+0.541×PI+0.604×Emax),Hosmer-Lemeshow x2=6.235,P=0.621.ROC curves analysis showed that AUC and 95％CI of Logistic regression model for predicting curative effect of microwave ablation were 0.793 and 0.712-0.874,respectively.Conclusion:Preoperative Dmax,PI and Emax are all independent risk factors affecting the curative effect of microwave ablation in patients with benign breast nodules.Logistic regression model based on multimodal ultrasound parameters can effectively predict the curative effect of microwave ablation,and effective intervention can be taken by the risk prediction model.关键词
多模态超声/乳腺良性结节/微波消融术/疗效/危险因素/预测模型Key words
multimodal ultrasound/benign breast nodule/microwave ablation/curative effect/risk factor/prediction model引用本文复制引用
刘晓璐,刘景萍,王谦,徐娟..术前多模态超声参数对乳腺良性结节微波消融术后疗效的预测价值[J].影像科学与光化学,2024,42(2):141-147,7.基金项目
河北省医学科学研究重点课题(20181232) （20181232）
