广州医药2024，Vol.55Issue(3)：231-235,5.DOI:10.3969/j.issn.1000-8535.2024.03.003
斑马鱼心血管疾病模型研究进展
Research progress of zebrafish cardiovascular disease models
摘要
Abstract
Cardiovascular disease is the leading cause of death in China.Between 2006 and 2019,the annual number of deaths due to cardiovascular diseases increased from 2.15 million to 3.28 million.Zebrafish has been widely used in medical research in recent years because of its small individual size,low cost,in vitro development,transparent body and high homology of genome with human.The zebrafish model is conducive to promoting basic research in the field of cardiovascular disease.Based on the review of previous studies,this paper focuses on the research progress of zebrafish model in gene screening,cardiac regeneration,drug screening,toxicity assessment and other aspects of cardiovascular diseases.关键词
斑马鱼/心血管疾病/心脏再生/药物筛选/毒性评估Key words
zebrafish/cardiovascular disease/heart regeneration/drug screening/toxicity assessment引用本文复制引用
董顺雨,张态..斑马鱼心血管疾病模型研究进展[J].广州医药,2024,55(3):231-235,5.基金项目
中国西南药用昆虫及蛛形类资源开发利用协同创新中心(CIC1803) （CIC1803）
