骨质疏松症"亏瘀致痿"的理论构建及临床应用OA北大核心CSTPCD

Osteoporosis(OP)is a metabolic bone disease characterized by an age-related loss of bone mass,destruction of bone microstructure,increased bone fragility and susceptibility to fracture.It is prevalent in postmenopausal women and middle-aged and elderly men and has an insidious onset.Most patients are diagnosed only after fracture,resulting in a significant consumption of medical resources.Based on the basic theories such as"kidney governing bone"and"kidney Qi deficiency",YAO Xinmiao's team in the Third Affiliated Hospital of Zhejiang Chinese Medical University innovatively puts forward the pathogenic theory of"flaccidity caused by deficiency and congestion"in OP,which holds that the pathogenesis of OP is the coexistence of deficiency and blood sta-sis,mixed with impotence.Under the guidance of this theory,it is believed that the"tonifying kidney,invigorating spleen and acti-vating blood circulation"method should be used to treat patients with OP based on syndrome differentiation.This method consists of three main aspects,including the simultaneous treatment of deficiency and blood stasis;tonifying kidney and invigorating spleen;strengthening both tendons and bones.The research team conducted a series of clinical and basic studies to explain the scientific con-notation of the OP rehabilitation strategy under the guidance of the theory of"flaccidity caused by deficiency and congestion"from different perspectives.