广西医科大学学报2024，Vol.41Issue(3)：328-336,9.DOI:10.16190/j.cnki.45-1211/r.2024.03.002
精神分裂症临床特征及影响因素
Clinical characteristics and influencing factors of schizophrenia
摘要
Abstract
Objective:To investigate the clinical characteristics and related influencing factors of schizophrenia.Methods:A total of 630 patients with schizophrenia in a Secondary Grade A psychiatric hospital in Tongling were recruited using convenience sampling method.Mini International Neuropsychiatric Interview(MINI),Clini-cian-Rated Dimensions of Psychosis Symptom Severity(CRDPSS)and Positive and Negative Syndrome Scale(PANSS)were used for diagnosis and assessment.Analysis of variance,Pearson correlation analysis and multiple linear regression were conducted with SAS 9.4 software for statistical analysis.Results:Patients with schizophre-nia who had different clinical characteristics showed variations in CRDPSS(F=22.46,P＜0.01)and PANSS(F= 7.99,P＜0.01)total scores.Patients with persistent deterioration had the highest total CRDPSS score(11.88±4.16)and PANSS score(75.63±23.95).Factors including age,sex,education level,family size,waist-to-hip ratio,marital status,working status,smoking,age of first diagnosis,age of first treatment,total number of schizophre-nia episodes,total number of hospitalizations,number of drug withdrawals,onset patterns and disease courses were associated with the total score of CRDPSS scale and PANSS scale,and with their every dimension score.Conclusion:Patients with schizophrenia with persistent deterioration have more severe symptoms.Waist-to-hip ratio,average daily cigarette smoking,number of drug withdrawals,total number of hospitalizations,and chronic onset are risk factors for severe symptoms in patients with schizophrenia.关键词
精神分裂症/危险因素/简明国际神经精神访谈/精神症状维度评定量表/阳性与阴性症状量表Key words
schizophrenia/risk factor/mini international neuropsychiatric interview/clinician-rated dimensions of psychosis symptom severity/positive and negative syndrome scale分类
医药卫生引用本文复制引用
赵来田,黄悦勤,黄俊捷,刘肇瑞,张婷婷,王帅,陈燕,常乐,徐小红,储文革..精神分裂症临床特征及影响因素[J].广西医科大学学报,2024,41(3):328-336,9.基金项目
国家重点研发计划(No.2017YFC0907800) （No.2017YFC0907800）
