中国健康心理学杂志2024,Vol.32Issue(4):503-509,7.DOI:10.13342/j.cnki.cjhp.2024.04.005
烟酸皮肤潮红反应用于抑郁症诊断的相关研究(综述)
Research related to niacin skin flushing response for the diagnosis of depression
摘要
Abstract
The main symptoms of depression are significant and persistent low mood,diminished interest,and lack of pleasure.Because depression is a mental illness with a high incidence,suicide rate,and relapse rate,it has recently drawn attention to how to accurately and effectively recognize and intervene in depression.The niacin skin flush test is a indirect technique for determining the amount of fatty acids present in cell membranes.Numerous studies have shown that depressed individuals have significantly lower niacin skin sensitivity,and the blunted niacin skin flush re-sponse is anticipated to serve as an additional bio-marker for the diagnosis of depression.This article analyzes and summarizes relevant literature from both domestic and international sources,focusing on the mechanism,detection methods,and research progress of the niacin skin flushing response in depression,in order to investigate the value of this method in assisting in the diagnosis of depression,and is expected to serve as a foundation for future research.关键词
抑郁症/辅助诊断/烟酸皮肤潮红反应/脂肪酸/膜磷脂代谢Key words
Depression/Complementary diagnosis/Niacin skin flush response/Fatty acids/Phospholipid breakdown in membranes分类
医药卫生引用本文复制引用
赵迎新,陈允恩..烟酸皮肤潮红反应用于抑郁症诊断的相关研究(综述)[J].中国健康心理学杂志,2024,32(4):503-509,7.基金项目
国家自然科学基金面上项目(编号:81971254) (编号:81971254)
科技创新2030-"脑科学与类脑研究"重大项目(编号:2021ZD0200700) (编号:2021ZD0200700)