化工学报2024，Vol.75Issue(2)：616-625,10.DOI:10.11949/0438-1157.20231210
氨基酸修饰的MOF-808催化降解神经毒剂的模拟酶性质研究
Study on the mimic enzymatic performance of amino acid modified MOF-808 for nerve agents decontamination
摘要
Abstract
A series of MOF-808-AA catalysts grafted with different amino acids were prepared by post-synthesis modification method.The effects of pore structure and pore microenvironment on the catalytic performance of nerve agent simulant were studied,and the mimic enzyme properties of MOF-808 and MOF-808-AA were further explored.The results showed that amino acid modification caused changes in the pore structure and pore microenvironment of MOF-808,thereby affecting the catalytic performance of the catalyst against the mimic agent.Among them,the hydrogen bond and hydrophobic interaction provided by the amino acid side chain improve the affinity of MOF-808-AA to the simulant.After amino acid grafting,the number of active metal sites in the original structure of MOF-808 decreased,resulting in the decrease in the degradation rate.The acidity and alkalinity of the amino acid side chain groups could lead to differences of the pore microenvironment.When the side chain is a basic group such as amino,the catalytic efficiency of the simulant decontamination is significantly improved.However,when the side chain is a carboxyl group,the catalytic efficiency is significantly reduced.关键词
MOF-808/氨基酸/后合成修饰/神经毒剂模拟剂Key words
MOF-808/amino acids/post-synthesis modification/nerve agent simulant分类
化学化工引用本文复制引用
刘克清,崔燕,于琼,陈立坤,郑永超,乔智威,郑禾..氨基酸修饰的MOF-808催化降解神经毒剂的模拟酶性质研究[J].化工学报,2024,75(2):616-625,10.基金项目
国家自然科学基金项目(21978058,21676094) （21978058,21676094）
广东省自然科学基金项目(2022A1515011446) （2022A1515011446）
