检验医学与临床2024，Vol.21Issue(7)：963-966,4.DOI:10.3969/j.issn.1672-9455.2024.07.021
血清β-hCG、AFP对前置胎盘合并胎盘植入的诊断价值
Diagnostic value of serum β-hCG and AFP in placenta previa complicating placenta implantation
赵朵朵 1王丽1
作者信息
- 1. 河南省三门峡市中心医院产科三病区,河南三门峡 472000
- 折叠
摘要
Abstract
Objective To investigate the value of serum β-human chorionic gonadotropin(β-hCG)and al-pha-fetoprotein(AFP)in the diagnosis of placenta previa complicating placenta implantation.Methods A to-tal of 84 patients with placenta previa visiting in this hospital from May 2020 to May 2022 were selected as study subjects and divided into the implantation group(38 cases)and non-implantation group(46 cases)ac-cording to clinical and postpartum pathological examination results.The prenatal serum β-hCG and AFP levels and prenatal ultrasound sign score were compared between the two groups and among the patients with differ-ent types of placenta implantation.The correlation between serum β-hCG and AFP levels with the type of pla-centa implantation and prenatal ultrasound sign score was analyzed.The receiver operating characteristic(ROC)curve was adopted to analyze the diagnostic value of prenatal serum β-hCG and AFP levels in placenta previa complicating placenta implantation.Results Compared with the non-implantation group,the prenatal serum β-hCG and AFP levels and ultrasound sign score in the implantation group were higher(P＜0.05).In the comparison of prenatal serum β-hCG and AFP levels among the patients with different types of placenta implantation:adhesive placenta＜implanted placenta＜penetrating placenta,and the differences in pairwise comparison were statistically significant(P＜0.05).The prenatal serum β-hCG and AFP levels were correla-ted with the ultrasound sign score and placental implantation type(P＜0.05).The area under the curve(AUC)of prenatal serum β-hCG and AFP levels in diagnosing placenta previa complicating placenta implanta-tion was 0.741 and 0.838 respectively,and AUC of the above two indicators combined diagnosis was 0.938,which was higher than that of single indicator.Conclusion Serum β-hCG and AFP levels have the high evalu-ation value in placenta previa combined with placenta implantation and the type of placenta implantation.关键词
前置胎盘/胎盘植入/β-人绒毛膜促性腺激素/甲胎蛋白/诊断Key words
placenta previa/placental implantation/β-human chorionic gonadotropin/alpha-fetopro-tein/diagnosis分类
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赵朵朵,王丽..血清β-hCG、AFP对前置胎盘合并胎盘植入的诊断价值[J].检验医学与临床,2024,21(7):963-966,4.
