检验医学与临床2024，Vol.21Issue(7)：996-998,3.DOI:10.3969/j.issn.1672-9455.2024.07.029
跌打生骨胶囊致重度药物性肝损伤的临床研究
Clinical study of severe drug induced liver injury caused by Dieda Shenggu Capsule
摘要
Abstract
Objective To analyze the adverse reactions in a case of severe drug-induced liver injury caused by taking Dieda Shenggu Capsules.Methods The Roussel Uclaf causality assessment method and Karch-La-sagna evaluation method were used for conducting the correlation evaluation,and the possible causes of liver injury caused by Dieda Shenggu Capsules were analyzed through literature retrieval.Results The patient had no history of liver underlying disease and developed severe liver injury after taking Dieda Shenggu Capsules alone.The causal correlation between Dieda Shenggu Capsules and liver injury is"very possible",and sarcandrae herba,salvia miltiorrhiza and rhizoma corydalis may be the main causes of liver injury.Conclusion In clinical use of Dieda Shenggu Capsules,attention should be paid to the internal components and course of treatment,especially the biochemical detection should be strengthened in the first 3 months of medication,the drug should be discontin-ued in time after liver injury occurs,and actively conduct symptomatic treatment.关键词
跌打生骨胶囊/药物性肝损伤/严重不良反应/肝功能/文献复习Key words
Dieda Shenggu Capsules/drug induced liver injury/severe adverse reaction/liver func-tion/literature review分类
医药卫生引用本文复制引用
谢欠,陈囡,廖玉芳,李娜..跌打生骨胶囊致重度药物性肝损伤的临床研究[J].检验医学与临床,2024,21(7):996-998,3.基金项目
重庆市黔江区科学技术局科技计划项目(黔科计2021014,黔科计2022037). （黔科计2021014,黔科计2022037）
