中国临床保健杂志2024，Vol.27Issue(1)：102-105,4.DOI:10.3969/J.issn.1672-6790.2024.01.021
乳腺癌保乳术后应用3D技术填充瘤腔进行适形放疗的临床研究
Clinical study of 3D tumor-cavitiy-filling intensity modulated radiation therapy for breast conserving surgery
摘要
Abstract
Objective To explore the target dose analysis,adverse reactions and cosmetic effects of 3D technol-ogy filling the tumor cavity for conformal radiotherapy after breast-conserving surgery.Methods Forty-eight patients with breast cancer admitted to the first affiliated hospital of Xi'an Jiaotong university from January 2021 to December 2022 were selected and divided into a 3D technology filling group(24 cases)and a control group(24 cases)according to different surgeries.All patients underwent radical breast cancer surgery,with only different breast-conserving methods,followed by APBI under IMRT plan.Results The CI and HI of conformal radiotherapy after breast-conserving surgery using 3D technology filling the tumor cavity were significantly higher than those of conventional breast-conserving surger-y.The lung and heart OAR doses,V5,V10,V20,V30,V40,and V50 in the 3D technology filling group were significantly lower than those in the conventional breast-conserving group.There was no significant difference in the incidence of skin damage,arrhythmia,bone marrow suppression,and gastrointestinal reaction between the two groups.The cosmetic effect of patients in the 3D technology filling group was significantly better than that in the conventional breast-conserving group.Conclusions The application of 3D technology filling the tumor cavity after breast-conserving surgery signifi-cantly enhances the cosmetic effect of the breast and does not affect the safety and effectiveness of radiotherapy.关键词
乳腺肿瘤/乳房切除术,区段/放射疗法,适形/乳房植入/化放疗Key words
Breast neoplasms/Mastectomy,segmental/Radiotherapy,conformal/Breast implantation/Chemora-diotherapy引用本文复制引用
李晓军,王和煦,张佳,王绩钊,朱财林,崔晓海..乳腺癌保乳术后应用3D技术填充瘤腔进行适形放疗的临床研究[J].中国临床保健杂志,2024,27(1):102-105,4.基金项目
陕西省自然科学基础研究计划项目(2021JM-281) （2021JM-281）
