刘辉 1刘明 2陈信义 3李道睿 4金璿 5段慧君6
作者信息
- 1. 北京中医药大学附属护国寺中医医院肿瘤科,北京 100035
- 2. 北京市西城区展览路医院普外科
- 3. 北京中医药大学东直门医院肿瘤科
- 4. 中国中医科学院广安门医院肿瘤科
- 5. 北京大学第一医院肿瘤科
- 6. 北京石景山医院老年病科
- 折叠
摘要
Abstract
Objective To investigate the changes of glucose metabolism in patients with digestive tumors under different inflammatory states and analyze the relationship and significance with hemoglobin(Hb).Methods Retrospec-tive analysis was performed among 80 patients with digestive tumors in Huguosi Hospital of Traditional Chinese Medicine Affiliated to Beijing University of Traditional Chinese Medicine from February 2021 to February 2022.The C-reactive protein(CRP)level was tested by particle enhanced immunotransmission turbidimetric method,the blood glucose was tested by glucose oxidase method,and the glycocated hemoglobin(HbA1c)level was tested by ion exchange and high performance liquid chromatography method,conventional methods for detecting Hb levels,and the analysis and correla-tion were carried out.Results According to the reference value of normal CRP level in our hospital,the patients were divided into 26 cases of normal CRP level group(group A),42 cases of mild to moderate increase in CRP level group(group B)and 12 cases of severe increase in CRP level group(group C).According to the WHO standard of diabetes diagnosis with HbA1c＞6.5％,the patients were divided into normal group(41 cases),high group(21 cases)and con-firmed group(18 cases).According to different CRP levels,the patients were divided into group A,group B and group C.CRP in the three groups showed a gradual increase(P＜0.05),FPG in group A and group B showed a gradual in-crease,FPG in group C showed a downward trend(P＞0.05),and Hb in groups A,B and C showed a decrease(P＜0.05)with the increase of CRP.According to different HbA1c levels,the patients were divided into normal group,high group and confirmed diabetes group.FPG level of the three groups showed a gradual increase,but no statistical signifi-cance(P＞0.05),Hb level showed a gradual decrease(P＜0.05),CRP level showed a downward trend after the in-crease(P＜0.05).Pearson correlation analysis showed that CRP was negatively correlated with Hb level(r=-0.315,P＜0.01),FPG was positively correlated with Hb and HbA1c(r=0.0.524,0.4025,P＜0.01),and Hb was negatively correlated with HbA1 c(r=-0.824,P＜0.001).Conclusion Most patients with digestive tumors will have abnormal glucose metabolism,and inflammation and Hb levels change significantly with abnormal glucose metabolism.关键词
消化系统肿瘤/炎症/血糖/血红蛋白类Key words
Digestive system neoplasms/Inflammation/Blood glucose/Hemoglobins
