临床肝胆病杂志2024，Vol.40Issue(4)：665-671,7.DOI:10.12449/JCH240404
丙型肝炎病毒感染与器官移植
Hepatitis C virus infection and organ transplantation
张莉 1胡鹏1
作者信息
- 1. 重庆医科大学附属第二医院感染病科,重庆 400016
- 折叠
摘要
Abstract
In recent years,rapid progress has been made in strategies for the prevention and treatment of hepatitis C virus(HCV)in organ transplant candidates and recipients,and although HCV infections no longer threaten transplantation outcomes in liver or non-hepatic solid organ transplantation,they remain a focus of research.Since hepatitis C is still a leading cause of death worldwide due to decompensated cirrhosis,liver failure,and hepatocellular carcinoma,appropriate organ transplantation is needed to improve survival rate and quality of life.With the increase in HCV-positive solid organ donors in recent years and the fact that the demand for organs still greatly exceeds organ supply,as well as the development of direct-acting antiviral agents,transplantation of HCV-viraemic organs into HCV-naïve recipients will significantly increase transplantation rates and reduce waitlist mortality.The efficacy of current HCV therapies has created an important opportunity to improve the survival rate of patients with end-organ failure by enhancing access to organ transplantation and reducing waitlist mortality.关键词
肝炎病毒属/抗病毒药/器官移植Key words
Hepacivirus/Antiviral Agents/Organ Transplantation引用本文复制引用
张莉,胡鹏..丙型肝炎病毒感染与器官移植[J].临床肝胆病杂志,2024,40(4):665-671,7.
