临床神经病学杂志2024，Vol.37Issue(2)：149-152,4.
肠道菌群介导脑卒中后功能修复的研究进展
Research progress on the critical role of gut microbiota mediating in functional recovery after stroke
摘要
Abstract
Stroke is the main cause of disability in adults.With the progress of stroke diagnosis and treatment technology,the mortality rate of stroke patients has decreased significantly,but its incidence keeps increasing,and there is an increasing number of stroke survivors develop chronic neurological disorders.At present,there is no clear drug to promote functional repair after stroke.Several studies have shown that gut microbiota can improve stroke prognosis by regulating neuroactive molecules and immune cell functions,enhancing neural network plasticity,and reducing neuroinflammation.Based on a review of previous studies,this paper describes the mechanism of action of gut microbiota on neural network plasticity and neuroinflammation after stroke and its impact on functional recovery after stroke and explores its clinical value and feasibility in improving neurological dysfunction after stroke.关键词
脑卒中/肠道菌群/神经可塑性/神经炎症Key words
stroke/gut microbiota/neuroplasticity/neuroinflammation分类
医药卫生引用本文复制引用
李颖,王一芳,林瑜辉,吴晋..肠道菌群介导脑卒中后功能修复的研究进展[J].临床神经病学杂志,2024,37(2):149-152,4.基金项目
江苏省自然科学基金(BK20191500) （BK20191500）
