农业科学研究2024，Vol.45Issue(1)：79-83,96,6.
RNAi——对抗细菌耐药的新途径
RNAi:A Novel Approach Against Bacterial Resistance
摘要
Abstract
Bacterial infections have become increasingly serious in recent years,posing significant threats to humans and livestock.Antibiotics remain the primary means of treating bacterial infections,yet the use of antibiotics enhances bacterial resistance.The emergence of RNA interference(RNAi)may offer hope in treating bacterial infections,as small RNA molecules can block the synthesis of resistance genes,thereby preventing their resistance and proliferation.Currently,this approach is more commonly implemented in viral infection studies in mammals and is also applied in treating bacterial infections in fish,but it has not been directly targeted at specific antibiotic-resistant genes.This paper aims to elucidate the mechanism of RNAi and its progress in research related to the prevention and control of resistant bacterial infections,further revealing the promising prospects of this technology in combating resistant pathogenic infections.关键词
RNA干扰技术/细菌感染/耐药性Key words
RNA interference/bacterial infection/resistance分类
农业科技引用本文复制引用
曹文迪,黄乙财,徐天乐..RNAi——对抗细菌耐药的新途径[J].农业科学研究,2024,45(1):79-83,96,6.基金项目
江苏省现代农业产业(奶牛)技术体系首席专家项目(JATS[2022]486) （奶牛）
国家自然科学基金青年项目(32102731) （32102731）
教育部农业与农产品安全国际合作联合实验室开放课题(JILAR-KF202204) （JILAR-KF202204）
