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MRI表观扩散系数在脑胶质瘤分级和IDH1基因分型中的临床意义

管龙 陈晨 沈蕾

中南医学科学杂志2024,Vol.52Issue(2):225-227,3.
中南医学科学杂志2024,Vol.52Issue(2):225-227,3.DOI:10.15972/j.cnki.43-1509/r.2024.02.016

MRI表观扩散系数在脑胶质瘤分级和IDH1基因分型中的临床意义

The clinical significance of MRI apparent diffusion coefficient in brain glioma grading and IDH1 genotyping

管龙 1陈晨 1沈蕾1

作者信息

  • 1. 中国人民解放军联勤保障部901 医院放射科,安徽合肥 230031
  • 折叠

摘要

Abstract

Aim To investigate the clinical significance of MRI apparent diffusion coefficient(ADC)in glioma grading and isocitrate dehydrogenase 1(IDH1)genotyping.Methods A total of 60 patients with glioma were retrospectively collected,and the ADC values of glioma with different grades and different IDH1 genotypes were compared.ROC curve was used to analyze the effi-cacy of ADC in the diagnosis of different grades of glioma.Results Compared with patients with low-grade glioma,the minimum ADC,average ADC,relative minimum ADC and relative average ADC of patients with high-grade glioma were significantly lower(P<0.05).ROC curve analysis showed that ADC had a good diagnostic value for glioma grading(P<0.05).Conclusion ADC has a good diagnostic value for glioma grading.

关键词

MRI/脑胶质瘤/分级/IDH1基因

Key words

MRI/brain glioma/grading/IDH1 gene

分类

医药卫生

引用本文复制引用

管龙,陈晨,沈蕾..MRI表观扩散系数在脑胶质瘤分级和IDH1基因分型中的临床意义[J].中南医学科学杂志,2024,52(2):225-227,3.

基金项目

安徽省自然科学基金项目(2008086QC155) (2008086QC155)

中南医学科学杂志

OACSTPCD

2095-1116

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