中南医学科学杂志2024，Vol.52Issue(2)：272-274,3.DOI:10.15972/j.cnki.43-1509/r.2024.02.029
脓毒症相关性脑病患者血清PCT、NSE、脑电双频指数变化及其临床意义
Change and clinical significance of serum PCT,NSE and bispectral index in patients with sepsis-related encephalopathy
摘要
Abstract
Aim To explore the changes of serum procalcitonin(PCT),neuron-specific enolase(NSE),and bispectral in-dex(BIS)in patients with sepsis-related encephalopathy(SAE)and its clinical significance.Methods 98 patients with sepsis were selected and divided into SAE group(n=42)and non-SAE group(n=56)according to the ICU delirium assessment scale.The serum levels of PCT,NSE,and BIS between two groups of patients were compared,the correlation between PCT,NSE,and BIS with Glasgow coma score(Glasgow)was analyzed,and their diagnostic efficacy in predicting SAE was evaluated.Furthermore,the risk factors that affect the occurrence of SAE was analyzed.Results The levels of PCT and NSE in the SAE group were higher than those in the non-SAE group,while the BIS and Glasgow score were lower than that in the non-SAE group(P<0.05).The serum levels of PCT and NSE in patients were negatively correlated with Glasgow score(P<0.001),while BIS was positively correlated with Glasgow score(P<0.001).Serum PCT,NSE,and BIS are independent risk factors for the occurrence of SAE,and PCT,NSE,and BIS have good predictive power for SAE.Conclusion Serum CT,NSE,and BIS in sepsis patients are independent risk factors for the occurrence of SAE and have important value in predicting the occurrence of SAE.关键词
脓毒症相关性脑病/降钙素原/神经元特异性烯醇化酶/脑电双频指数Key words
sepsis-related encephalopathy/procalcitonin/neuron specific enolase/bispectral index分类
医药卫生引用本文复制引用
佟心,王伟,邸芳芳..脓毒症相关性脑病患者血清PCT、NSE、脑电双频指数变化及其临床意义[J].中南医学科学杂志,2024,52(2):272-274,3.基金项目
廊坊市科学技术项目(2019013025) （2019013025）
