上海针灸杂志2024，Vol.43Issue(4)：400-404,5.DOI:10.13460/j.issn.1005-0957.2023.13.0016
运动针法配合药物及功能训练治疗强直性脊柱炎的疗效观察
Therapeutic observation of exercise-based acupuncture combined with medication and functional training for ankylosing spondylitis
摘要
Abstract
Objective To observe the clinical efficacy of exercise-based acupuncture plus intravenous infusion of Infliximab and functional training in treating ankylosing spondylitis(AS)and its effects on the lumbar range of motion(ROM),pain,and serum galectin-3 level in the patients.Method Ninety-four AS patients were randomized into a treatment group and a control group,with 47 cases in each group.The control group received the intravenous infusion of Infliximab and functional training,based on which the treatment group received additional exercise-based acupuncture.Before and after the treatment,the lumbar ROM,Bath ankylosing spondylitis disease activity index(BASDAI),visual analog scale(VAS)score,Bath ankylosing spondylitis functional index(BASFI),and serum levels of galectin-3,C-reactive protein(CRP),and erythrocyte sedimentation rate(ESR)were observed.The clinical efficacy and safety evaluation were compared between the two groups.Result After the treatment,the lumbar ROM and serum galectin-3 level increased significantly in both groups,and the BASDAI,VAS,and BASFI scores dropped,as well as the CRP and ESR levels,all showing statistical significance(P＜0.05).After the treatment,the lumbar ROM and serum galectin-3 level were higher in the treatment group than in the control group,and the BASDAI,VAS,and BASFI scores and CRP and ESR levels were lower in the treatment group,presenting statistical significance(P＜0.05).In the treatment group,the total effective rate and adverse reaction rate during the intervention were 89.4%and 10.6%,respectively,versus 68.1%and 31.9%in the control group,and the between-group differences were statistically significant(P＜0.05).Conclusion Exercise-based acupuncture plus intravenous infusion of Infliximab and functional training can produce valid efficacy in treating AS.It can effectively relieve pain,increase the serum galectin-3 level,and reduce the CRP and ESR levels,with a high safety rating.关键词
针刺疗法/运动针法/脊柱炎,强直性/针药并用/功能训练/半乳糖凝集素3Key words
Acupuncture therapy/Exercise-based acupuncture/Spondylitis,Ankylosing/Acupuncture medication combined/Functional training/Galectin-3分类
医药卫生引用本文复制引用
郭纯良,吴佳,张伟,严晓琴..运动针法配合药物及功能训练治疗强直性脊柱炎的疗效观察[J].上海针灸杂志,2024,43(4):400-404,5.基金项目
四川省中医药管理局资助项目(2021MS357) （2021MS357）
