上海针灸杂志2024，Vol.43Issue(4)：405-410,6.DOI:10.13460/j.issn.1005-0957.2024.04.0405
温针灸治疗腰椎间盘突出症的疗效观察及对炎症因子的影响
Observation on the efficacy of needle-warming moxibustion for lumbar disc herniation and its effect on inflammatory factors
摘要
Abstract
Objective To observe the clinical efficacy of needle-warming moxibustion for lumbar disc herniation and its effect on inflammatory factors.Method Ninety-five patients with lumbar disc herniation were enrolled and allocated,using a random number table,to an observation group(48 cases)and a control group(47 cases).The control group received conventional treatment and the observation group received needle-warming moxibustion in addition.The clinical therapeutic effects were compared between the two groups.The TCM syndrome score,the Oswestry disability index(ODI)score and the Japanese Orthopaedic Association(JOA)score were recorded in the two groups before and after treatment.The levels of inflammatory factors[interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β),substance P(SP),5-hydroxytryptamine(5-HT)and prostaglandin E2(PGE2)]were measured in the two groups before and after treatment.Result The total efficacy rate was 93.8%in the observation group,which was higher than 78.7%in the control group with a statistically significant difference(P＜0.05).After treatment,the TCM syndrome scores,the ODI score and the JOA score decreased in the two groups compared with those before treatment(P＜0.05)and were lower in the observation group than those in the control group(P＜0.05).After treatment,IL-1β,TNF-α,IL-6,SP,5-HT and PGE2 levels decreased in the two groups compared with those before treatment(P＜0.05)and were lower in the observation group than those in the control group(P＜0.05).Conclusion On the basis of conventional treatment,needle-warming moxibustion can heighten the clinical therapeutic effect,relieve the clinical symptoms,improve lumbar spine function and reduce inflammatory factors and pain mediator levels in treating lumbar disc herniation.关键词
针刺疗法/温针疗法/针药并用/腰椎间盘突出症/腰痛/炎症因子/疼痛介质Key words
Acupuncture therapy/Needle warming therapy/Acupuncture medication combined/Lumbar disc herniation/Low back pain/Inflammatory factor/Pain mediator分类
医药卫生引用本文复制引用
邓利萍,彭艳,范小春..温针灸治疗腰椎间盘突出症的疗效观察及对炎症因子的影响[J].上海针灸杂志,2024,43(4):405-410,6.基金项目
南充市哲学社会科学重点研究基地名老中医医案研究中心2022年度资助项目(YAZX22-ZD-03) （YAZX22-ZD-03）
南充市中医医院四川省中医药管理局研发资金项目(2021MS374) （2021MS374）
南充市科技局项目(22YYJCYJ0033) （22YYJCYJ0033）
