上海针灸杂志2024，Vol.43Issue(4)：411-415,5.DOI:10.13460/j.issn.1005-0957.2024.04.0411
针药并用治疗膝骨关节炎的疗效观察及对疼痛和关节功能的影响
Clinical efficacy observation of acupuncture combined with Chinese medication on knee osteoarthritis and its influence on pain and joint function
摘要
Abstract
Objective To observe the clinical effect of acupuncture at Siguan points and Xi-cleft points combined with Juan Bi Tang in the treatment of knee osteoarthritis and its influence on joint pain and joint function.Method A total of 100 patients with knee osteoarthritis were randomly divided into a control group(50 cases)and an observation group(50 cases).The control group was treated with Juan Bi Tang,and the observation group was treated with acupuncture at Siguan points and Xi-cleft points on the basis of the treatment of the control group.The clinical efficacy was compared between the two groups.The pain visual analog scale(VAS)score,Western Ontario and McMaster Universities osteoarthritis index(WOMAC)score and American Hospital for Special Surgery(HSS)score before and after treatment were compared between the two groups.The bone metabolism indexes[serum osteocalcin(OC)and osteoclastogenesis inhibitory factor(OPG)]and inflammatory factor indexes[serum interleukin-6(IL-6),tumor necrosis factor-α(TNF-α)and interleukin-1(IL-1)]were observed before and after treatment in the two groups.Result The total effective rate of the observation group was 94.0%,which was higher than 72.0%of the control group(P＜0.05).After treatment,the VAS scores,WOMAC total scores and levels of serum IL-6,TNF-α and IL-1 were lower than those before treatment in the two groups(P＜0.05),and the scores and levels were lower in the observation group than those in the control group(P＜0.05).Compared before treatment,the HSS scores and serum levels of OC and OPG were increased in the two groups(P＜0.05),and the scores and levels were higher in the observation group than those in the control group(P＜0.05).Conclusion Acupuncture at Siguan points and Xi-cleft points combined with Juan Bi Tang in the treatment of knee osteoarthritis can effectively reduce knee pain,improve knee joint function and bone metabolism,and reduce inflammatory factors.The curative effect is better than Chinese medication alone.关键词
针刺疗法/针药并用/穴,合谷/穴,太冲/穴,郄/骨关节炎,膝/疼痛Key words
Acupuncture therapy/Acupuncture medication combined/Acupoint,Hegu(LI4)/Acupoint,Taichong(LR3)/Acupoint,Xi-cleft/Osteoarthritis,knee/Pain分类
医药卫生引用本文复制引用
蔡建刚,仲慧,王利平,张树芸,马银菲..针药并用治疗膝骨关节炎的疗效观察及对疼痛和关节功能的影响[J].上海针灸杂志,2024,43(4):411-415,5.基金项目
张家口市重点研发计划项目(2221166D) （2221166D）
