上海针灸杂志2024，Vol.43Issue(4)：362-367,6.DOI:10.13460/j.issn.1005-0957.2023.13.0030
改良无痛麦粒化脓灸配合药物治疗支气管哮喘慢性持续期疗效观察
Therapeutic observation of modified painless wheat-grain sized suppurative moxibustion plus medication in treating chronic persistent bronchial asthma
摘要
Abstract
Objective To observe the clinical efficacy of modified painless wheat-grain sized suppurative moxibustion plus medication in treating bronchial asthma(BA)in the chronic persistent stage and its effects on the levels of interleukin(IL)-6,IL-10,and tumor necrosis factor-α(TNF-α).Method Ninety patients with chronic persistent BA were randomized into a treatment group and a control group,with 45 cases in each group.The control group received Salmeterol xinafoate and Fluticasone propionate powder for inhalation,based on which the treatment group was given modified grain-sized suppurative moxibustion at back-Shu points.Before and after the treatment,the two groups were observed for changes in the asthma control test(ACT)score,pulmonary function indexes[forced expiratory volume in 1 second(FEV1),forced vital capacity(FVC),and peak expiratory flow(PEF)],symptom scores of traditional Chinese medicine(panting,coughing,and wheezing sound),and serum inflammatory factor levels(IL-6,IL-10,and TNF-α).The clinical efficacy was compared between the two groups.Result After the treatment,the two groups showed an increase in the ACT score,pulmonary function indexes,and IL-10 level,and a decrease in the clinical symptom scores and the levels of IL-6 and TNF-α;the changes were all statistically significant(P＜0.05).After the intervention,the ACT score,pulmonary function indexes,and IL-10 level were higher in the treatment group than in the control group,and the clinical symptom scores and the levels of IL-6 and TNF-α were lower in the treatment group;the between-group differences were statistically significant(P＜0.05).The total effective rate was 92.9%in the treatment group,notably higher than 80.5%in the control group,and the between-group difference was statistically significant(P＜0.05).Conclusion The modified painless wheat-grain sized suppurative moxibustion plus medication is effective in treating BA in the chronic persistent stage.It can benefit the patient's pulmonary function and improve the serum levels of IL-6,IL-10,and TNF-α and clinical symptoms.关键词
灸法/哮喘/艾炷灸/直接灸/化脓灸/肺功能/炎性因子Key words
Moxibustion/Asthma/Moxa cone moxibustion/Direct moxibustion/Suppurative moxibustion/Pulmonary function/Inflammatory factors分类
医药卫生引用本文复制引用
郭金依,邵智愚,陈怡文,高慧霞,韩琳,刘颖,苏秀贞..改良无痛麦粒化脓灸配合药物治疗支气管哮喘慢性持续期疗效观察[J].上海针灸杂志,2024,43(4):362-367,6.基金项目
山东省中医药管理局齐鲁医派中医药特色技术推广项目[鲁卫函(2020)132号] （2020）
潍坊市卫生健康委员会科研项目(WFZYY2022-4-015) （WFZYY2022-4-015）
