张晓静 1孙佶英 1肖卫忠 1张丽丽 1任宁 1杨振华1
作者信息
摘要
Abstract
Objective:To explore the application effect of cognitive screening scales commonly used in memory clinics of tertiary Grade A general hospitals,so as to provide a reference for the diagnosis of neurocognitive disorders.Methods:A total of 155 patients who were admitted to the memory clinic from October 2020 to May 2022 and complained of memory loss were selected.After initial diagnosis by a neurologist,they were prescribed cognitive impairment screening with the consent of the patients.After the appointment,the Chinese version of ACE-Ⅲ,MMSE,CDT4,MoCA,AD8 and ADL scales were screened by nurses with cognitive screening training qualification.The patients brought the cognitive screening results,relevant laboratory and imaging examination to the neurology department for diagnosis and treatment.Results:Among the 155 patients,72 were in the normal group,38 were in the MCI group,and 45 were in the dementia group.The correlation between five cognitive screening scales and related factors showed that age,years of education,degree of cognitive impairment were more significantly correlated with the Chinese version of ACE-Ⅲ and MoCA.The area under the ROC curve of Chinese ACE-Ⅲ,MMSE,MoCA and AD8 in MCI group was 0.698-0.788,and the specificity of MoCA,Chinese ACE-Ⅲ and AD8 in MCI diagnosis was 78.9%,76.3%and 73.7%,respectively.The sensitivity was 70.8%,58.3%and 56.9%,respectively.The area under ROC curve of the Chinese version of ACE-Ⅲ,MMSE and MoCA was between 0.915-0.931.The sensitivity of MMSE,Chinese version of ACE-Ⅲ and MoCA for dementia diagnosis was 91.7%,84.7%and 83.3%,and the highest specificity was 86.7%,84.4%and 84.4%,respectively.Conclusion:MoCA and the Chinese version of ACE-Ⅲ should be used in the memory clinic of ClassⅢGrade A general hospitals for elderly patients with memory loss and certain educational background.The accuracy of cognitive screening scale in MCI screening was MoCA>Chinese ACE-Ⅲ>AD8,and the accuracy of dementia screening was MMSE>Chinese ACE-Ⅲ>MoCA.关键词
认知功能/评估工具/老年人/轻度认知障碍/痴呆/量表Key words
cognitive function/evaluation tools/the elderly/mild cognitive impairment/dementia/scale
