特产研究2024，Vol.46Issue(2)：30-35,6.DOI:10.16720/j.cnki.tcyj.2024.041
菟丝子盐炙前后对肾阳虚模型大鼠精子活力的影响
Effect of Cuscutae Semen on Sperm Motility in Rats with Kidney Yang Deficiency before and after Salt Burning
摘要
Abstract
To study the effect of Cuscutae semen on sperm motility in rats with kidney yang deficiency before and after salt burning.The method of hydrocortisone muscle injection was used to establish the rat kidney yang deficiency model,and the rats with Cuscutae semen raw products,salt-processed products,commercially available salt-processed Cuscutae semen water extract,and Jin kui Shen qi pills were used to gavage the stomach of rats with"kidney yang deficiency"for 14 days,recording the organ index,sperm density and sperm motility of testicles,epididymis and other organs,sperm density and sperm motility,observing testicular histopathological sections,measuring serum testosterone levels and acid phosphatase(ACP),succinate dehydrogenase(SDH),total superoxide dismutase(T-SOD),glutathione(GSH),The content of malondialdehyde(MDA)and other contents was compared to study the effect of Cuscutae semen salted on sperm motility in rats with renal yang deficiency.Comparing with the model group,Cuscutae semen salt-processed product,commercial product and raw wat-er extract could improve sperm motility,reducing testicular and epididymal index,improving the pathological symptoms of spermatogenic tubules and spermatogenic cells at all levels,the average values of testosterone,ACP,SDH,T-SOD and GSH in the salt-processed group were higher than those in the commercial group and the raw group,and the MDA was lower than that in the commercial group and the raw group.Cuscutae semen raw products and salt burnt products water extract can improve the sperm motility of hydrocortisone-induced kidney yang deficiency rats by enzymes that affect spermatogenesis and oxidative stress response,and the salt burnt products has a better effect.This study preliminarily discusses the processing mechanism of salt dodder,which provides further theoretical support for the scientific processing.关键词
菟丝子/盐炙/肾阳虚/精子活力Key words
Cuscutae semen/salt burning process/kidney yang deficiency/sperm motility分类
医药卫生引用本文复制引用
陈曦,赵林涛,李雅娟,韩昕,李凡,王卫锋,李莎莎,李芳..菟丝子盐炙前后对肾阳虚模型大鼠精子活力的影响[J].特产研究,2024,46(2):30-35,6.基金项目
陕西省中医药管理局中医药全省性专款专项项目(2021-QYZL-01) （2021-QYZL-01）
