特产研究2024，Vol.46Issue(2)：99-102,4.DOI:10.16720/j.cnki.tcyj.2024.049
参柏舒心颗粒HPLC指纹图谱建立
HPLC Fingerprint Study of Shenbaishuxin Granules
摘要
Abstract
To establish the HPLC fingerprints of Shenbaishuxin granules.The waters C18(4.6 mm×250 mm,5 μm)was used,the mobile phase was acetonitrile-0.05％trifluoroacetic acid solution,the flow rate was 1.0 mL/min with gradient elution,the column temperature was 40 ℃,the detection wavelength was 254 nm.The HPLC fingerprint of ten batches of Shenbaishuxin granules was determined.The simi-larity evaluation was performed by the"Chinese Herbal Chromatographic Similarity Evaluation System(2012 edition)"software.The HPLC fingerprint of Shenbaishuxin granules was established.A total of 25 common peaks were determined and five component were identified.The similarities of ten samples were higher than 0.93,and the method was reliable.This study the analytical method showd feasibility and good separation effect,providing a scientific basis for improving the quality control of Shenbaishuxin granules.关键词
参柏舒心颗粒/指纹图谱/相似度评价Key words
Shenbaishuxin granules/fingerprints/similarity evaluation分类
医药卫生引用本文复制引用
刘爽,王翠竹,李平亚,姜维铮,杜秀娟..参柏舒心颗粒HPLC指纹图谱建立[J].特产研究,2024,46(2):99-102,4.基金项目
吉林省科技发展计划项目(20190304107YY) （20190304107YY）
