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阻塞性睡眠呼吸暂停对男性生殖功能的影响OACSTPCD

Effects of obstructive sleep apnoea on male reproductive function

中文摘要英文摘要

男性不育与环境因素、不良生活习惯、肥胖、代谢综合征以及染色体异常等密切相关,阻塞性睡眠呼吸暂停(OSA)是其中一个重要的独立危险因素.研究发现,OSA的发病率逐年上升,OSA作为男性不育的一种可逆因素,应当及时诊断并尽早进行治疗.本文就OSA与睾酮水平、勃起功能障碍(ED)、精液质量、男性不育等方面的研究进展进行综述,总结其对男性生殖功能的影响及其潜在机制.

Male infertility is closely related to environmental factors,poor living habits,obesity,metabolic syndrome and chromosome abnormalities,among which obstructive sleep apnoea(OSA)is an important independent risk factor.Studies have found that the incidence of OSA is increasing year by year.As a reversible factor of male infertility,OSA should be diagnosed and treated as early as possible.This article reviews the research progress of OSA and its impact on testosterone level,erectile dysfunction,semen quality,and male infertility.It also summarizes the effects of OSA on male reproductive function and potential mechanisms.

王泽豪;张庆丰;杨菁

武汉大学人民医院生殖医学中心暨湖北省辅助生殖技术与胚胎发育临床研究中心,武汉 430060

临床医学

男性不育症男性生殖功能阻塞性睡眠呼吸暂停睡眠剥夺间歇缺氧

Male infertilityMale Reproductive functionObstructive sleep apnoeaSleep deprivationIntermittent hypoxia

《生殖医学杂志》 2024 (004)

外泌体源LncRNA SNHG12/STAT3/G-CSF轴通过介导滋养细胞与巨噬细胞的交互对话维持正常妊娠的机制研究

559-562 / 4

国家自然科学基金项目(82101749)

10.3969/j.issn.1004-3845.2024.04.023

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