纤维素科学与技术2024，Vol.32Issue(1)：28-38,11.DOI:10.16561/j.cnki.xws.2024.01.12
功能化细菌纤维素纳米晶复合聚氨酯医用抗菌涂层的制备及性能研究
Preparation and Properties of Functional Bacterial Cellulose Nanocrystalline Polyurethane Composite Antibacterial Coating for Medical Purposes
摘要
Abstract
The infection of medical implants is one of the difficult problems in clinical treatment.Therefore,it is crucial to conduct research on medical coatings that exhibit long-term stable antibacterial effects.In this study,oxidized modified bacterial cellulose nanocrystals were prepared using the comminution-oxidation method,and a cationic compound called biguanide was chemically grafted onto them to create a new nanometer-sized antibacterial material known as NBC-BG.By combining NBC-BG with polyurethane(PU),a medical antibacterial coating named PU-NBC-BG was developed.The structural properties of these coatings with varying proportions were investigated through various material characterization techniques.Furthermore,the antibacterial experiment demonstrated that the PU-NBC-BG coating exhibits excellent and enduring antibacterial properties as well as an effective anti-biofilm effect,making it highly promising for application in the field of medical devices.关键词
细菌纤维素纳米晶/双胍/长效抗菌/医用涂层Key words
bacterial cellulose nanocrystals/biguanide/long-acting antibacterial/medical coating分类
化学化工引用本文复制引用
杨惠仪,张栗杨,丁蒙,贺玮,谢亚杰,乔堃,郑裕东..功能化细菌纤维素纳米晶复合聚氨酯医用抗菌涂层的制备及性能研究[J].纤维素科学与技术,2024,32(1):28-38,11.基金项目
国家自然科学基金(52273119,51973018) （52273119,51973018）
北京市科委项目(Z191100002019017) （Z191100002019017）
北京市自然科学基金(2222067,L222035) （2222067,L222035）
北京科技大学 2022年度研究生教育教学改革面上项目(2023JGC004). （2023JGC004）
