医疗卫生装备2023，Vol.44Issue(10)：49-54,6.DOI:10.19745/j.1003-8868.2023206
不同叠加方法下非小细胞肺癌2次计划累积剂量的差异比较
Comparative analysis of cumulative doses after two planned radiotherapy treatments for non-small cell lung cancer with different superposition methods
徐珊 1刘强 1任必勇 1周艳玲 2张隆彬1
作者信息
- 1. 重庆大学附属三峡医院肿瘤科,重庆 404100
- 2. 重庆三峡医药高等专科学校,重庆 404100
- 折叠
摘要
Abstract
Objective To analyze the cumulative doses after two planned radiotherapy treatments for non-small cell lung cancer with direct superposition,rigid superposition and deformation superposition.Methods Twenty-four non-small cell lung cancer patients undergoing radical radiotherapy at some hospital were selected,who went through simulation positioning and radiotherapy treatment with modified plan after receiving 20 radiotherapy sessions.The cumulative dose after two planned radiotherapy treatments was calculated and compared with three methods including direct superposition,rigid superposition of Monaco treatment planning system and deformation superposition of MIM software.Results Direct superposition had the target dose the highest among those calculated by the three methods,followed by rigid superposition and deformation superposition in turn,and both rigid superposition and deformation superposition had significant differences with direct superposition(all P＜0.05).Among the three methods direct superposition had the V5,V10 and V15 of lung and Dmean of heart and esophagus the lowest,the V20 of lung similar to that by deformation superposition while lower than that by rigid superposition and the remained indexes the highest;of the cumulative doses calculated by rigid superposition only the V5 of lung and Dmean of heart were lower than those by deformation superposition.Pairwise comparisons between the three methods showed only the differences between the Dmax of esophagus were statistically significant(all P＜0.05).Conclusion The three superposition methods have differences when used to calculate the dose-volume parameters of the target areas and organs at risk,and different superposition methods have to be taken into considerations during clinical operations to avoid over-or under-assessment of the doses to tumor and normal tissue.[Chinese Medical Equipment Journal,2023,44(10):49-54]关键词
非小细胞肺癌/图像配准/直接叠加法/刚性配准叠加法/形变配准叠加法Key words
non-small cell lung cancer/image registration/direct superposition/rigid superposition/deformation superposition分类
医药卫生引用本文复制引用
徐珊,刘强,任必勇,周艳玲,张隆彬..不同叠加方法下非小细胞肺癌2次计划累积剂量的差异比较[J].医疗卫生装备,2023,44(10):49-54,6.
