眼科新进展2024，Vol.44Issue(4)：291-296,6.DOI:10.13389/j.cnki.rao.2024.0057
超广域SS-OCTA联合超广角激光扫描眼底成像对糖尿病视网膜病变的诊断价值
Diagnostic value of ultra-wide field swept-source optical coherence tomo-graphy angiography combined with ultra-wide field scanning laser ophthal-moscopy in diabetic retinopathy
摘要
Abstract
Objective To investigate the detection rate and grading diagnostic value of ultra-wide field swept-source optical coherence tomography angiography(UWF SS-OCTA)combined with ultra-wide field scanning laser ophthalmoscopy(UWF SLO)in diabetic retinopathy(DR)lesions.Methods In this cross-sectional study,diabetic patients attending the Ophthalmology Department of Sichuan Provincial Peoples Hospital were recruited.All participants underwent UWF SS-OC-TA,UWF SLO and fundus fluorescein angiography to detect DR lesions,including microaneurysms(MA),intraretinal hem-orrhages(IRH),nonperfusion areas(NPAs),intraretinal microvascular abnormalities(IRMAs),venous beading(VB),neovascularization elsewhere(NVE),neovascularization of the optic disc(NVD),and vitreous hemorrhage(VH).The re-sults of the combination of three imaging examinations(triple imaging)were used as the standards,evaluating the detec-tion rate and severity grading consistency in DR lesions of pairwise combinations of different imaging modalities.Results A total of 101 patients(175 eyes)were included.Compared with the triple imaging results,the detection rates of UWF SS-OCTA combined with UWF SLO for MA,IRH,NPAs,IRMAs,NVE,NVD and VH were 91％,83％,77％,69％,27％,10％and 12％,respectively,with Kappa values of 0.812,1.000,1.000,1.000,0.986,0.970 and 1.000.Compared with the triple imaging results,the combination of UWF SS-OCTA and UWF SLO demonstrated excellent consistency in grading the severity of DR(Kappa=0.943).Conclusion UWF SS-OCTA combined with UWF SLO can accurately identify MA,IRH,NPAs,IRMAs,NVE,NVD and VH,demonstrating high accuracy in DR screening and grading diagnosis,making it suitable for large-scale screening and management of DR in clinical practice.关键词
超广域扫频源光学相干断层扫描血管成像/超广角激光扫描眼底成像/荧光素眼底血管造影/糖尿病性视网膜病变Key words
ultra-wide field swept-source optical coherence tomography angiography/ultra-wide field scanning laser ophthalmoscopy/fundus fluorescein angiography/diabetic retinopathy分类
医药卫生引用本文复制引用
毛明珠,黎梦宇,韦丁杨,陈丽,刘逸,李杰,钟捷..超广域SS-OCTA联合超广角激光扫描眼底成像对糖尿病视网膜病变的诊断价值[J].眼科新进展,2024,44(4):291-296,6.基金项目
四川省科技计划项目(编号:2022YFS0234) （编号:2022YFS0234）
四川省自然科学基金项目(编号:2022NSFSC1352,2023NSFSC0592) （编号:2022NSFSC1352,2023NSFSC0592）
四川省人民医院基金项目(编号:2021QN13) （编号:2021QN13）
四川省人类疾病遗传学研究重点实验室2021年开放课题(编号:2021kflx008) （编号:2021kflx008）
四川省卫生健康委员会医学科技项目(编号:21PJ077) （编号:21PJ077）
四川干部保健科研项目(编号:川干研ZH2024-201,川干研ZH2019-201) （编号:川干研ZH2024-201,川干研ZH2019-201）
