中国临床药理学与治疗学2024，Vol.29Issue(5)：520-526,7.DOI:10.12092/j.issn.1009-2501.2024.05.006
基于ClinicalTrials.gov数据库的子宫内膜异位症临床研究多维度分析
Multidimensional analysis of endometriosis clinical trials based on the ClinicalTrials.gov database
摘要
Abstract
AIM:To perform a multidimensional analysis of the clinical study characteristics of endo-metriosis based on the ClinicalTrials.gov,providing comprehensive and objective information for re-searchers,clinicians,and clinical pharmacists.METHODS:A thorough investigation was conduct-ed on clinical trials related to endometriosis,regis-tered on the ClinicalTrials.gov from its inception to October 20,2023.Relevant trial data were extract-ed and statistically analyzed using bibliometrics and comparative research methods.RESULTS:A to-tal of 667 endometriosis clinical studies were regis-tered globally,showing an annual increase.The United States(127 trials),France(70 trials),and Ita-ly(57 trials)had the highest number of registered trials.Interventional studies were predominant(416 trials,62.4%),followed by observational stud-ies(251 trials,37.6%).Within interventional stud-ies,drug therapy was the primary intervention(223 trials,53.6%).Despite endometriosis being a female condition,male subjects were also consid-ered,with 6 trials specifically requiring male partici-pants and 37 trials not restricting gender.Compa-nies/corporations were the main funding sources,while public and governmental organizations pro-vided relatively less funding.CONCLUSION:Clinical trial research on endometriosis is in a phase of growth,with drug therapy being the main treat-ment approach.However,there is a relative lack of investment and attention from public funds and governmental organizations.关键词
子宫内膜异位症/临床研究注册/Clini-calTrials.gov/多维度分析Key words
endometriosis/clinical study registra-tion/ClinicalTrials.gov/multidimensional analysis分类
医药卫生引用本文复制引用
张保寅,杨文辉,刘青蓝,王琛,武婧,刘倩,孙楠..基于ClinicalTrials.gov数据库的子宫内膜异位症临床研究多维度分析[J].中国临床药理学与治疗学,2024,29(5):520-526,7.基金项目
河南省医学科技攻关联合共建项目(LHGJ20190402) （LHGJ20190402）
博士科研基金项目(2021038) （2021038）
