中国中西医结合外科杂志2024，Vol.30Issue(2)：238-242,5.DOI:10.3969/j.issn.1007-6948.2024.02.018
解毒承气汤治疗术后早期炎性肠梗阻的临床观察
Clinical observation of Jiedu Chengqi decoction in the treatment of early postoperative inflammatory intestinal obstruction
摘要
Abstract
Objective To investigate the efficacy of Jiedu Chengqi decoction combined with somatostatin and intestinal obstruction catheter in the treatment of inflammatory intestinal obstruction and the effect on immune inflammation and gastrointestinal function recovery.Methods 80 patients with inflammatory ileus admitted to our hospital from June 2020 to June 2023 were selected and divided into two groups by random number table method.The control group(40 cases)was treated with somatostatin and intestinal obstruction catheter,and the observation group was treated with Jiedu Chengqi decoction combined with somatostatin and intestinal obstruction catheter.The effects,gastrointestinal function recovery,immune inflammation,quality of life and adverse reactions were compared between the two groups.Results The total effective rate of observation group was 90.00％,which was higher than that of control group 62.50％(P＜0.05).The recovery time of bowel sound,the time of disappearance of abdominal symptoms,the time of first anal exhaust,the time of first anal defecation in the observation group were shorter than those in the control group(P＜0.05),and the daily gastrointestinal decompression drainage volume and abdominal circumference reduction length were greater than those in the control group(P＜0.05).After treatment,the proportion of Thl in peripheral blood,serum IFN-γ level and GIQLI score in the observation group were higher than those in the control group(P＜0.05),and the proportion of Th2 in peripheral blood and serum IL-4 level in the control group were lower than those in the control group(P＜0.05).Conclusion Jiedu Chengqi decoction combined with somatostatin and intestinal obstruction catheter in the treatment of inflammatory intestinal obstruction can promote the recovery of gastrointestinal function,improve immunity,inhibit inflammatory response,and improve clinical efficacy and quality of life of patients.关键词
炎症性肠梗阻/解毒承气汤/生长抑素/肠梗阻导管/免疫/炎症/胃肠功能Key words
Inflammatory intestinal obstruction/Jiedu Chengqi decoction/somatostatin/intestinal obstruction catheter/immunity/inflammation/gastrointestinal function分类
医药卫生引用本文复制引用
刘井瑞,杨晶娜,袁大为,王华..解毒承气汤治疗术后早期炎性肠梗阻的临床观察[J].中国中西医结合外科杂志,2024,30(2):238-242,5.基金项目
秦皇岛市科技局项目(202301A029) （202301A029）
