中国比较医学杂志2024，Vol.34Issue(2)：122-128,7.DOI:10.3969/j.issn.1671-7856.2024.02.015
经皮给药系统皮肤模型的研究进展
Overview of in vitro skin models of transdermal drug delivery systems
摘要
Abstract
Skin modeling of transdermal drug delivery system refers to experimental models that mimic the structure and function of human skin to explore and evaluate absorption,penetration,and efficacy of medicines in transdermal drug delivery.It provides an alternative to traditional human skin experiments and reduces the use of human skin in medical research,which is convenient,controllable,and cost effective.For skin models of transdermal drug delivery systems,this article introduces commonly used animal skin models,artificial skin models,and recombinant human skin models from the perspective of the transdermal absorption pathway of medicines,and analyzes their advantages,disadvantages,and applications so provide references the research and development of transdermal formulations and topical therapies.关键词
经皮给药系统/皮肤模型/应用特点Key words
transdermal drug delivery system/skin model/application characteristics分类
医药卫生引用本文复制引用
刘沿,胡小垒,许可洪,赵海荣,巫秀美,杨自忠,张成桂,赵昱,高鹏飞..经皮给药系统皮肤模型的研究进展[J].中国比较医学杂志,2024,34(2):122-128,7.基金项目
国家自然科学基金(82160798,81960712,81260676) （82160798,81960712,81260676）
云南省重大科技专项计划—生物资源数字化开发应用(202002AA100007) （202002AA100007）
中国国家留学基金(201708535007). （201708535007）
