中国比较医学杂志2024，Vol.34Issue(2)：161-166,6.DOI:10.3969/j.issn.1671-7856.2024.02.020
环状RNA在帕金森病中作用机制研究进展
Advances in the mechanism-of-action of circRNA in Parkinson's disease
摘要
Abstract
PD is a neurodegenerative disease characterized by degenerative death of dopaminergic neurons in the substantia nigra,exhibiting a range of motor and non-motor symptoms with serious effects on quality of life.circRNA is a covalently closed-loop non-coding RNA that plays a major role in PD progression.This article reviews the involvement of circRNA in oxidative stress,regulation of transcription,neuroinflammation,autophagy,and α-synuclein.关键词
帕金森病/circRNA/氧化应激/神经炎症/生物标志物Key words
Parkinson's disease/circRNA/oxidative stress/neuroinflammation/biomarkers分类
医药卫生引用本文复制引用
刘娟,李彦杰,秦合伟,马璐瑶,赵楠楠,徐振华..环状RNA在帕金森病中作用机制研究进展[J].中国比较医学杂志,2024,34(2):161-166,6.基金项目
河南省中医药拔尖人才培养项目(豫中医科教[2018]35号) （豫中医科教[2018]35号）
中原英才计划中原青年拔尖人才项目(豫科[2021]1号) （豫科[2021]1号）
河南省高等学校重点科研项目(19A360024). （19A360024）
