中国医药科学2024，Vol.14Issue(6)：155-158,4.DOI:10.20116/j.issn2095-0616.2024.06.36
PCT、CRP、WBC和NEC对肾综合征出血热早期诊断的价值
Values of PCT,CRP,WBC,and NEC for early diagnosis of hemorrhagic fever with renal syndrome
摘要
Abstract
Objective To explore the value of procalcitonin(PCT),C-reactive protein(CRP),white blood cells(WBC),and neutrophils(NEC)in the early diagnosis of hemorrhagic fever with renal syndrome.Methods A total of 227 patients with hemorrhagic fever with renal syndrome treated at Hongqi Hospital Affiliated to Mudanjiang Medical University from September 2022 to July 2023 were selected as the subjects.According to the severity,the subjects were divided into mild,moderate,severe,and critically severe groups.According to the stages,the subjects were divided into fever stage,hypotension shock stage,oliguria stage,polyuria stage,and recovery stage.200 healthy individuals who underwent physical examinations at the Medical Examination Center of Hongqi Hospital Affiliated to Mudanjiang Medical University during the same period were selected as the reference(healthy group).Indicators such as PCT,CRP,WBC,and NEC in patients and healthy individuals were detected.Results The PCT,CRP,WBC,and NEC detection indicators of patients with hemorrhagic fever with renal syndrome were higher than those of the healthy group(P＜0.05).In terms of PCT and NEC detection indicators,the results of patients in oliguria stage were greater than those in hypotension shock stage,fever stage,polyuria stage,and recovery stage,targeting patients with different stages.The detection results of patients in hypotension shock stage were greater than those in fever stage,polyuria stage,and recovery stage.The detection results of patients in the fever stage were greater than those in the polyuria and recovery stages.The detection results of patients in the polyuria stage were greater than those of patients in the recovery stage.In terms of CRP and WBC detection indicators,the results of the two groups of patients in oliguria and hypotension shock stage were higher than those in fever,polyuria,and recovery stages.The detection results of patients in the fever stage were greater than those in the polyuria and recovery stages.The detection results of patients in the polyuria stage were greater than those of patients in the recovery stage.In terms of PCT and CRP detection indicators,the results of critically ill patients were higher than those of severe,medium,and mild patients,targeting patients with different subtypes.The detection results for severe patients were greater than those for moderate and mild patients.In terms of WBC and NEC indicators,the detection results of critically ill patients were greater than those of severe,medium,and mild patients.The detection results for severe patients were greater than those for moderate and mild patients.The detection results of medium patients were greater than those of mild patients.The differences are statistically significant(P＜0.05).Conclusion PCT and NEC indicators can serve as a basis for determining stages to a certain extent.WBC and NEC indicators can serve as a basis for determining severity to a certain extent.关键词
肾综合征出血热/降钙素原/C反应蛋白/白细胞/中性粒细胞Key words
Hemorrhagic fever with renal syndrome/PCT/CRP/WBC/NEC分类
医药卫生引用本文复制引用
王惠琦,黄晶晶,张晓东,罗烨,李慧影..PCT、CRP、WBC和NEC对肾综合征出血热早期诊断的价值[J].中国医药科学,2024,14(6):155-158,4.基金项目
牡丹江市科学技术局:牡丹江市应用技术研究与开发计划项目(HT2022NS091) （HT2022NS091）
黑龙江省省属高等学校基本科研业务费科研项目(2020-KYYWF-0753). （2020-KYYWF-0753）
