中国医药科学2024，Vol.14Issue(6)：159-163,5.DOI:10.20116/j.issn2095-0616.2024.06.37
参芪地黄汤治疗慢性肾脏病临床效果及安全性的meta分析
Meta-analysis of the clinical efficacy and safety of Shenqi Dihuang Decoction in the treatment of chronic kidney disease
摘要
Abstract
Objective To systematically evaluate the clinical efficacy and safety of Shenqi Dihuang Decoction in the treatment of chronic kidney disease(CKD).Methods Randomized controlled trials(RCT)for the treatment of CKD with Shenqi Dihuang Decoction were retrieved in databases such as CNKI,Wanfang,VIP,CBM,and PubMed,with the retrieval time limit from the establishment of the database to February 2023.RevMan 5.4 software was used for quality evaluation and meta-analysis.Results A total of 10 studies were included,involving and 722 patients.The meta-analysis results showed that the total effective rate and endogenous creatinine clearance rate of the test group were higher than those of the control group,while the serum creatinine,blood urea nitrogen,24-hour urine protein quantification,and adverse reaction rate of the test group were lower than those of the control group,with differences were statistically significant(P＜0.05).Conclusion Shenqi Dihuang Decoction has good clinical efficacy and safety in the treatment of CKD,not limited to deficiency of qi and yin.关键词
参芪地黄汤/慢性肾脏病/随机对照试验/meta分析Key words
Shenqi Dihuang Decoction/Chronic kidney disease/Randomized controlled trials/meta-analysis分类
医药卫生引用本文复制引用
葛瑞,郑艳辉..参芪地黄汤治疗慢性肾脏病临床效果及安全性的meta分析[J].中国医药科学,2024,14(6):159-163,5.基金项目
第四批江苏省名老中医药专家传承工作室项目:孔薇工作室(苏中医科教[2021]7号) （苏中医科教[2021]7号）
江苏省南京市科技计划项目(201803018) （201803018）
南京中医药大学自然科学基金项目(XZR2021049). （XZR2021049）
