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艾司氯胺酮复合丙泊酚应用于无痛宫腔镜检查术中的麻醉效果OACSTPCD

Anesthesia effect of esketamine combined with propofol in painless hysteroscopy

中文摘要英文摘要

目的 探讨无痛宫腔镜检查术中艾司氯胺酮复合丙泊酚的麻醉效果.方法 选取2020年4月至2022年4月在我院行无痛宫腔镜检查术的168例患者作为研究对象,按照随机数字表法将患者分为对照组(静脉泵注100 mg曲马多+2.5 mg/kg丙泊酚)和观察组(静脉泵注0.5 mg/kg艾司氯胺酮+1 mg/kg丙泊酚),每组84例.比较2组患者术后麻醉复苏效果、苏醒后疼痛程度、术后苏醒时间、追加丙泊酚例数、丙泊酚总用量、不良反应及治疗满意度.结果 2组患者术后15 min、30 min的改良Aldrete评分比较差异无统计学意义(P>0.05);观察组术后5 min的改良Aldrete评分高于对照组(P<0.05).苏醒后2组患者的VAS评分均升高,且观察组患者苏醒后5 min、15 min、30 min的VAS评分均低于对照组(P<0.05).观察组患者术后苏醒时间短于对照组,追加丙泊酚例数及丙泊酚总用量少于对照组(P<0.05).2组不良反应发生率比较差异无统计学意义(26.18%vs.14.28%;χ2=3.687,P=0.055).对照组的治疗满意度低于观察组(76.19%vs.92.86%;χ2=8.919,P=0.003).结论 艾司氯胺酮复合丙泊酚应用于无痛宫腔镜检查术患者可提高术中麻醉及术后镇痛效果,减少丙泊酚使用剂量,有利于患者早期麻醉复苏,且不良反应少,安全性好,治疗满意度高.

Objective To explore the anesthesia effect of esketamine combined with propofol in painless hysteroscopy.Methods A total of 168 patients who underwent painless hysteroscopy in our hospital from April 2020 to April 2022 were selected as the study subjects.According to random number table,they were divided into the control group(100 mg tramadol+2.5 mg/kg propofol injected intravenously)and the observation group(0.5 mg/kg esketamine +1 mg/kg propofol injected intravenously),with 84 cases in each group.The effect of postoperative anesthesia resuscitation,pain degree after recovery,postoperative recovery time,number of additional propofol cases,total dosage of propofol,adverse reactions and treatment satisfaction of patients in the two groups were compared.Results There was no statistically significant difference in the modified Aldrete score 15 minutes and 30 minutes after operation between patients in the two groups(P>0.05).The modified Aldrete score 5 minutes after operation in the observation group was higher than that in the control group(P<0.05).The VAS scores of patients in the two groups were increased after regaining consciousness,and the VAS scores of patients 5 minutes,15 minutes and 30 minutes after regaining consciousness the observation group were lower than those in the control group(P<0.05).The postoperative recovery time in the observation group was shorter than that in the control group,and number of additional propofol cases and total dosage of propofol were less than those in the control group(P<0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(26.18%vs.14.28%;χ2=3.687,P=0.055).The treatment satisfaction in the control group was lower than that in the observation group(76.19%vs.92.86%;χ2=8.919,P=0.003).Conclusion Esketamine combined with propofol in painless hysteroscopy patients can improve intraoperative anesthesia and postoperative analgesic effects,reduce the dosage of propofol.It is conducive to early anesthesia recovery of patients,and has less adverse reactions,good safety,high treatment satisfaction.

李欢颜;李朋;陈凌君

永州市中心医院麻醉科,湖南 永州 425000永州市中心医院耳鼻咽喉头颈外科,湖南 永州 425000

临床医学

宫腔镜检查艾司氯胺酮曲马多丙泊酚麻醉

hysteroscopyesketaminetramadolpropofolanesthesia

《局解手术学杂志》 2024 (004)

318-321 / 4

10.11659/jjssx.03E023107

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